| Friday 7th November 2025 Premier Division |
||
| City of Liverpool | 1-3 | AFC Liverpool |
| Wednesday 5th November 2025 Staffordshire Senior Cup 2nd Round |
||
| Eccleshall | 3-0 | Abbey Hulton United |
| Wednesday 5th November 2025 Premier Division |
||
| AFC Liverpool | 1-1 | Prestwich Heys |
| South Liverpool | 3-0 | Charnock Richard |
| Tuesday 4th November 2025 Derbyshire Senior Cup 2nd Round |
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| New Mills | 5-0 | Ashbourne |
| Shirebrook Town | 0-5 | Glossop North End |
| Tuesday 4th November 2025 Premier Division |
||
| Atherton LR | 3-2 | Longridge Town |
| Cheadle Town | 0-1 | West Didsbury & Chorlton |
| Euxton Villa | 3-3 | FC Isle of Man |
| Irlam | P-P | Chadderton |
| Postponed due to Waterlogged Pitch | ||
| Padiham | 4-1 | Abbey Hey |
| Ramsbottom United | 4-1 | Barnoldswick Town |
| Tuesday 4th November 2025 Walsall Senior Cup 1st Round |
||
| Wolverhampton Casuals | 1-4 | Coleshill Town |
| Monday 3rd November 2025 Premier Division |
||
| Stockport Town | 1-3 | Burscough |
| Monday 3rd November 2025 First Division North |
||
| Daisy Hill | 3-1 | Colne |
| Saturday 1st November 2025 The Isuzu FA Vase 1st Round |
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| Holker Old Boys | 2-1 | Wythenshawe |
| Saturday 1st November 2025 First Division North |
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| AFC Blackpool | 1-0 | Steeton |
| Ashton Town | 4-2 | Thornton Cleveleys |
| Daisy Hill | 2-1 | Squires Gate |
| Darwen FC | 3-1 | Ashton Athletic |
| Fulwood Amateurs | 4-3 | Droylsden |
| Maghull | 1-0 | Maine Road |
| MSB Woolton | 3-3 | Colne |
| Nelson | P-P | Garstang |
| Postponed due to Waterlogged Pitch | ||
| Sat 8th Nov 2025 The Isuzu FA Vase 2nd Round |
|||
| Albion Sports | 3-2 | Holker Old Boys | |
| Barnoldswick Town | 1-2 | Winsford United | |
| Brigg Town | 1-2 | West Didsbury & Chorlton | |
| Burscough | 3-1 | Ashton Town | |
| Charnock Richard | 0-2 | Nelson | |
| Cheadle Town | 0-0 | North Shields | |
| Crook Town | 0-4 | Ramsbottom United | |
| Droylsden | 4-2 | Northwich Victoria | |
| Liversedge | 2-1 | Atherton LR | |
| Prestwich Heys | 0-0 | Irlam | |
| Redcar Town | 0-2 | Chadderton | |
| South Liverpool | 4-0 | Barton Town | |
| Premier Division | |||
| Abbey Hey | 1-2 | Wythenshawe | |
| FC Isle of Man | 1-2 | Pilkington | |
| FC St Helens | 1-1 | Padiham | |
| Longridge Town | 4-3 | Euxton Villa | |
| Stockport Town | 1-2 | Glossop North End | |
| First Division North | |||
| AFC Blackpool | 2-0 | Ashton Athletic | |
| Colne | 4-1 | Darwen FC | |
| Garstang | 2-2 | Maghull | |
| Squires Gate | 1-2 | MSB Woolton | |
| Steeton | 1-1 | Daisy Hill | |
| Thornton Cleveleys | 1-2 | Bacup Borough | |
| First Division South | |||
| Barnton | 2-1 | Foley Meir | |
| Cammell Laird 1907 | 1-3 | New Mills | |
| Eccleshall | 1-0 | Ashville | |
| Market Drayton Town | 0-0 | Cheadle Heath Nomads | |
| Runcorn Town | 3-1 | Stockport Georgians | |
| Sandbach United | 4-1 | Allscott Heath | |
| Shawbury United | 2-3 | Alsager Town | |
| Telford Town | 2-2 | Wolverhampton Sporting Community | |
| Wolverhampton Casuals | 3-0 | Haughmond | |
Saturday KO 15:00, Midweek KO 19:45 unless stated
| Sunday 9th November 2025 The Isuzu FA Vase 2nd Round |
| Yarm & Eaglescliffe v Fulwood Amateurs |
| Monday 10th November 2025 First Division North |
| Maine Road v Ashton Town |
| Tuesday 11th November 2025 Premier Division |
| Atherton LR v Irlam |
| Barnoldswick Town v Longridge Town |
| Cheadle Town v Chadderton |
| Padiham v Charnock Richard |
| Prestwich Heys v Abbey Hey |
| Wythenshawe v Ramsbottom United |
| Euxton Villa v AFC Liverpool (20:00) |
| Tuesday 11th November 2025 First Division North |
| Colne v AFC Blackpool |
| Tuesday 11th November 2025 First Division South |
| Wolverhampton Casuals v Shawbury United |
| Wednesday 12th November 2025 The Edward Case Cup 1st Round North |
| Nelson v MSB Woolton |
| Played at MSB Woolton |
| Wednesday 12th November 2025 Premier Division |
| West Didsbury & Chorlton v City of Liverpool |
| Wednesday 12th November 2025 First Division North |
| Bacup Borough v Holker Old Boys (20:00) |
| Thursday 13th November 2025 Cheshire Senior Cup 1st Round |
| Crewe Alexandra v Barnton (20:00) |
| Friday 14th November 2025 Premier Division |
| Atherton LR v Prestwich Heys |
| FC St Helens v South Liverpool |
| Saturday 15th November 2025 The Edward Case Cup 2nd Round North |
| Ashton Town v Darwen FC |
| Maghull v Bacup Borough |
| Maine Road v AFC Blackpool |
| Saturday 15th November 2025 The Edward Case Cup 2nd Round South |
| Barnton v Ashville |
| Played at Ashville |
| Runcorn Town v Stafford Town |
| Sandbach United v Cheadle Heath Nomads |
| Telford Town v Stockport Georgians |
| Saturday 15th November 2025 Premier Division |
| AFC Liverpool v Longridge Town |
| Burscough v Glossop North End |
| Chadderton v City of Liverpool |
| Charnock Richard v Cheadle Town |
| Irlam v Abbey Hey |
| Ramsbottom United v Pilkington |
| Stockport Town v Barnoldswick Town |
| Wythenshawe v Euxton Villa |
| FC Isle of Man v West Didsbury & Chorlton (18:00) |
| Saturday 15th November 2025 First Division North |
| Ashton Athletic v Garstang |
| Colne v Thornton Cleveleys |
| Squires Gate v Steeton |
| Saturday 15th November 2025 First Division South |
| Allscott Heath v Market Drayton Town |
| Foley Meir v Shawbury United |
| Haughmond v Cammell Laird 1907 |
| Premier Division | P | GD | Pts | |
| 1 | Ramsbottom United | 19 | 32 | 47 |
| 2 | Padiham | 20 | 27 | 47 |
| 3 | West Didsbury & Chorlton | 20 | 21 | 43 |
| 4 | Wythenshawe | 17 | 10 | 37 |
| 5 | Burscough | 19 | 14 | 35 |
| 6 | Irlam | 18 | 13 | 34 |
| 7 | FC St Helens | 20 | 11 | 33 |
| 8 | South Liverpool | 19 | 5 | 33 |
| 9 | Chadderton | 16 | 18 | 29 |
| 10 | Longridge Town | 19 | 2 | 28 |
| 11 | Atherton LR | 18 | 11 | 27 |
| 12 | Pilkington | 21 | -18 | 26 |
| 13 | Stockport Town | 20 | -5 | 25 |
| 14 | Prestwich Heys | 18 | -1 | 24 |
| 15 | Glossop North End | 21 | -13 | 23 |
| 16 | Cheadle Town | 16 | 0 | 21 |
| 17 | Barnoldswick Town | 17 | -15 | 21 |
| 18 | Charnock Richard | 18 | 2 | 20 |
| 19 | Euxton Villa | 19 | -10 | 18 |
| 20 | FC Isle of Man | 21 | -25 | 17 |
| 21 | AFC Liverpool | 18 | -11 | 16 |
| 22 | City of Liverpool | 17 | -12 | 16 |
| 23 | Abbey Hey | 19 | -22 | 12 |
| 24 | Litherland REMYCA | 20 | -34 | 4 |
| First Division North | P | GD | Pts | |
| 1 | Maghull | 13 | 12 | 24 |
| 2 | Nelson | 9 | 1 | 21 |
| 3 | Droylsden | 13 | 8 | 20 |
| 4 | Darwen FC | 12 | 5 | 20 |
| 5 | Ashton Town | 12 | 0 | 20 |
| 6 | Bacup Borough | 12 | -1 | 20 |
| 7 | Holker Old Boys | 10 | 10 | 19 |
| 8 | AFC Blackpool | 10 | 7 | 19 |
| 9 | Fulwood Amateurs | 11 | 5 | 18 |
| 10 | Daisy Hill | 14 | -2 | 17 |
| 11 | Steeton | 14 | -6 | 16 |
| 12 | Colne | 11 | 1 | 15 |
| 13 | Maine Road | 12 | 6 | 14 |
| 14 | Thornton Cleveleys | 12 | 2 | 14 |
| 15 | MSB Woolton | 13 | -7 | 14 |
| 16 | Squires Gate | 13 | -7 | 12 |
| 17 | Garstang | 11 | -18 | 8 |
| 18 | Ashton Athletic | 12 | -16 | 7 |
| First Division South | P | GD | Pts | |
| 1 | Runcorn Town | 16 | 33 | 39 |
| 2 | Eccleshall | 15 | 13 | 33 |
| 3 | Telford Town | 15 | 17 | 30 |
| 4 | Barnton | 16 | 12 | 29 |
| 5 | Stockport Georgians | 16 | 12 | 29 |
| 6 | Sandbach United | 15 | 11 | 29 |
| 7 | Stafford Town | 14 | 18 | 27 |
| 8 | New Mills | 15 | 14 | 26 |
| 9 | Allscott Heath | 15 | 8 | 22 |
| 10 | Ashville | 15 | 5 | 22 |
| 11 | Foley Meir | 16 | 0 | 22 |
| 12 | Cheadle Heath Nomads | 17 | -3 | 18 |
| 13 | Alsager Town | 16 | -5 | 17 |
| 14 | Cammell Laird 1907 | 15 | -14 | 15 |
| 15 | Wolverhampton Casuals | 14 | -9 | 14 |
| 16 | Market Drayton Town | 17 | -13 | 14 |
| 17 | Shawbury United | 16 | -29 | 14 |
| 18 | Haughmond | 17 | -29 | 9 |
| 19 | Wolverhampton Sporting Community | 16 | -41 | 5 |
Tables correct as at Sat 8th Nov 2025
