| Saturday 10th December 2022 | The Macron Cup 3rd Rnd | ||
| 13:00 |  Congleton Town v Lower Breck  | The Cleric Stadium | |
| 14:00 |  Euxton Villa P-P FC St Helens  | Jim Fowler Memorial Ground | |
| Postponed due to frozen pitch | |||
| 14:00 |  Northwich Victoria P-P Barnoldswick Town  | Wincham Park | |
| Postponed due to frozen pitch | |||
| 14:00 |  South Liverpool v Abbey Hulton United  | Jericho Lane | |
| 14:00 |  Squires Gate v Wythenshawe Town  | The Brian Addison Stadium | |
| 15:00 |  Kendal Town P-P New Mills  | Parkside Road Stadium | |
| Postponed due to frozen pitch | |||
| 15:00 |  Pilkington v Avro  | The Arcoframe Stadium | |
| Saturday 10th December 2022 | The Edward Case Cup 3rd Rnd | ||
| 15:00 |  Eccleshall P-P Abbey Hey  | Pershall Park | |
| Postponed due to frozen pitch | |||
| Saturday 10th December 2022 | Premier Division | ||
| 13:30 |  Winsford United P-P Bury AFC  | Barton Stadium | |
| Postponed due to frozen pitch | |||
| 16:30 |  FC Isle of Man v Litherland REMYCA  | The Bowl | |
| Saturday 10th December 2022 | First Division North | ||
| 12:45 |  Holker Old Boys P-P Atherton LR  | The Handmark Engineering Stadium | |
| Postponed due to frozen pitch | |||
| 13:00 |  Nelson P-P Garstang  | Little Wembley | |
| Postponed due to frozen pitch | |||
| 15:00 |  Chadderton P-P Ashton Town  | The Falcon Fire Stadium | |
| Postponed due to frozen pitch | |||
| 15:00 |  Ilkley Town v AFC Blackpool  | MPM Stadium | |
| 15:00 |  Runcorn Town P-P Cleator Moor Celtic  | Viridor Community Stadium | |
| Postponed due to frozen pitch | |||
| Saturday 10th December 2022 | First Division South | ||
| 13:30 |  Brocton v Ellesmere Rangers  | Silkmore Lane Sports Ground | |
| 14:00 |  Alsager Town P-P Cheadle Town  | Woodpark Stadium | |
| Postponed due to frozen pitch | |||
| 14:00 |  Maine Road P-P Foley Meir  | Brantingham Road | |
| Postponed due to frozen pitch | |||
| 14:00 |  Rocester P-P Stockport Town  | Hillsfield | |
| Postponed due to frozen pitch | |||
| 14:00 |  Stockport Georgians P-P Ashville  | Cromley Road | |
| Postponed due to frozen pitch | |||
| 14:00 |  Wythenshawe Amateurs P-P Stafford Town  | Selco Builders Warehouse Community Stadium | |
| Postponed due to frozen pitch | |||
| Saturday 10th December 2022 | Wirral Senior Cup 2nd Rnd | ||
| 14:00 |  Cammell Laird 1907 v Higher Bebington Kelma  | Prabhu Ventures Ltd Arena | |
| Sunday 11th December 2022 | The Macron Cup 3rd Rnd | ||
| 15:00 |  Barnton v Bacup Borough  | Townfield | |
| Monday 12th December 2022 | First Division North | ||
| 19:45 |  Daisy Hill v Euxton Villa | New Sirs | |
| Monday 12th December 2022 | First Division South | ||
| 19:45 | Maine Road v Stockport Town | Brantingham Road | |
| Tuesday 13th December 2022 | Premier Division | ||
| 19:45 | Bury AFC v Charnock Richard  | Neuven Stadium | |
| 19:45 |  Longridge Town v Ashton Athletic  | The Recycling Lives Ground | |
| 19:45 | Northwich Victoria v AFC Liverpool  | Wincham Park | |
| 19:45 |  West Didsbury & Chorlton v Kendal Town | Step Places Stadium | |
| 20:00 | Barnoldswick Town v Congleton Town | Silentnight Stadium | |
| Tuesday 13th December 2022 | First Division North | ||
| 19:45 | Ashton Town v Pilkington | Hebs Group Stadium | |
| 19:45 | Chadderton v FC St Helens | The Falcon Fire Stadium | |
| 20:00 | Holker Old Boys v Ilkley Town | The Handmark Engineering Stadium | |
| Tuesday 13th December 2022 | First Division South | ||
| 19:45 | Abbey Hulton United v Sandbach United  | Drayton Beaumont Park | |
| 19:45 | Alsager Town v Eccleshall | Woodpark Stadium | |
| 19:45 | Cammell Laird 1907 v Barnton | Prabhu Ventures Ltd Arena | |
| 19:45 | Cheadle Town v Foley Meir | Park Road Stadium | |
| 19:45 | Stockport Georgians v Wythenshawe Amateurs | Cromley Road | |
| 20:00 | Abbey Hey v Rocester | The Abbey Stadium | |
| 20:00 | Brocton v Ashville | Silkmore Lane Sports Ground | |
| Wednesday 14th December 2022 | Premier Division | ||
| 20:00 | Squires Gate v FC Isle of Man | The Brian Addison Stadium | |
| Wednesday 14th December 2022 | First Division North | ||
| 20:00 | Bacup Borough v AFC Blackpool | Brian Boys West View Stadium | |
| Friday 16th December 2022 | Premier Division | ||
| 20:00 | Lower Breck v Padiham  | Anfield Sports Community Centre | |
| Saturday 17th December 2022 | Premier Division | ||
| 13:30 |  Irlam v Prestwich Heys  | The RG3 Digital Stadium | |
| 14:00 | Ashton Athletic v Squires Gate | Brocstedes Park | |
| 15:00 |  Burscough v Winsford United | The Community Ground | |
| 15:00 | Congleton Town v Bury AFC | The Cleric Stadium | |
| 15:00 | Kendal Town v Avro | Parkside Road Stadium | |
| 15:00 | Litherland REMYCA v Barnoldswick Town | Litherland Sports Park | |
| 15:00 | Longridge Town v Charnock Richard | The Recycling Lives Ground | |
| 15:00 |  Vauxhall Motors v Northwich Victoria | The vanEupen Arena | |
| 15:00 | Wythenshawe Town v West Didsbury & Chorlton | Ericstan Park | |
| 18:00 | FC Isle of Man v AFC Liverpool | The Bowl | |
| Saturday 17th December 2022 | First Division North | ||
| 15:00 | AFC Blackpool v Steeton  | Mechanics Ground | |
| 15:00 | Bacup Borough v Holker Old Boys | Brian Boys West View Stadium | |
| 15:00 | Daisy Hill v Ashton Town | New Sirs | |
| 15:00 |  Darwen FC v Chadderton | WEC Group Anchor Ground | |
| 15:00 | Euxton Villa v Pilkington | Jim Fowler Memorial Ground | |
| 15:00 | FC St Helens v Nelson | Windleshaw Sports Ground | |
| 15:00 | Garstang v Atherton LR | The Riverside | |
| 15:00 | Runcorn Town v Ilkley Town | Viridor Community Stadium | |
| 15:00 | South Liverpool v Cleator Moor Celtic | Jericho Lane | |
| Saturday 17th December 2022 | First Division South | ||
| 15:00 | Alsager Town v Rocester | Woodpark Stadium | |
| 15:00 | Ashville v Eccleshall | Villa Park | |
| 15:00 | Barnton v Abbey Hulton United | Townfield | |
| 15:00 | Brocton v Stockport Georgians | Silkmore Lane Sports Ground | |
| 15:00 |  Cheadle Heath Nomads v Wythenshawe Amateurs | The Heath | |
| 15:00 | Ellesmere Rangers v Cheadle Town | Beech Grove Stadium | |
| 15:00 | Foley Meir v Cammell Laird 1907 | McIntosh Arena | |
| 15:00 | Maine Road v Abbey Hey | Brantingham Road | |
| 15:00 | New Mills v Stafford Town | Church Lane | |
| 15:00 | Stockport Town v Sandbach United | Stockport Sports Village | |
| Tuesday 20th December 2022 | Premier Division | ||
| 19:45 | Burscough v Congleton Town | The Community Ground | |
| 19:45 | Prestwich Heys v Longridge Town | Adie Moran Park | |
| 19:45 | Squires Gate v Bury AFC | The Brian Addison Stadium | |
| Tuesday 20th December 2022 | First Division North | ||
| 19:45 | Chadderton v Runcorn Town | The Falcon Fire Stadium | |
| 19:45 | FC St Helens v Darwen FC | Windleshaw Sports Ground | |
| Tuesday 20th December 2022 | First Division South | ||
| 19:45 | Abbey Hulton United v Alsager Town | Drayton Beaumont Park | |
| 19:45 | New Mills v Brocton | Church Lane | |
| 20:00 | Eccleshall v Wythenshawe Amateurs | Pershall Park | |
| Tuesday 20th December 2022 | Lancashire Challenge Trophy 2nd Rnd | ||
| 19:45 | Charnock Richard v Padiham | Mossie Park | |
| Wednesday 21st December 2022 | Premier Division | ||
| 19:45 | Barnoldswick Town v Wythenshawe Town | Silentnight Stadium | |
| 19:45 | Northwich Victoria v Irlam | Wincham Park | |
| Wednesday 21st December 2022 | First Division North | ||
| 19:45 | Pilkington v Bacup Borough | The Arcoframe Stadium | |
| Saturday 24th December 2022 | Premier Division | ||
| 15:00 | Northwich Victoria v Bury AFC | Wincham Park | |
| Saturday 24th December 2022 | First Division North | ||
| 15:00 | Cleator Moor Celtic v Bacup Borough | McGrath Park | |
| Monday 26th December 2022 | Premier Division | ||
| 13:30 | AFC Liverpool v Vauxhall Motors | The Marine Travel Arena | |
| 14:00 | Northwich Victoria v Congleton Town | Wincham Park | |
| 15:00 | Bury AFC v Wythenshawe Town | Neuven Stadium | |
| 15:00 | Irlam v Ashton Athletic | The RG3 Digital Stadium | |
| 15:00 | Padiham v Barnoldswick Town | Ruby Civil Arena | |
| 15:00 | Prestwich Heys v Lower Breck | Adie Moran Park | |
| 15:00 | Squires Gate v Burscough | The Brian Addison Stadium | |
| 15:00 | West Didsbury & Chorlton v Charnock Richard | Step Places Stadium | |
| 15:00 | Winsford United v Litherland REMYCA | Barton Stadium | |
| Monday 26th December 2022 | First Division North | ||
| 15:00 | Atherton LR v Daisy Hill | Crilly Park | |
| 15:00 | Chadderton v Bacup Borough | The Falcon Fire Stadium | |
| 15:00 | Cleator Moor Celtic v Holker Old Boys | McGrath Park | |
| 15:00 | Darwen FC v Nelson | WEC Group Anchor Ground | |
| 15:00 | Euxton Villa v AFC Blackpool | Jim Fowler Memorial Ground | |
| 15:00 | Pilkington v FC St Helens | The Arcoframe Stadium | |
| 15:00 | Runcorn Town v South Liverpool | Viridor Community Stadium | |
| Monday 26th December 2022 | First Division South | ||
| 12:00 | Stafford Town v Brocton | Evans Park | |
| 12:30 | Cheadle Town v Cheadle Heath Nomads | Park Road Stadium | |
| 14:00 | Wythenshawe Amateurs v Maine Road | Selco Builders Warehouse Community Stadium | |
| 15:00 | Cammell Laird 1907 v Ashville | Prabhu Ventures Ltd Arena | |
| 15:00 | Eccleshall v Ellesmere Rangers | Pershall Park | |
| 15:00 | Foley Meir v Alsager Town | McIntosh Arena | |
| 15:00 | Rocester v Abbey Hulton United | Hillsfield | |
| 15:00 | Sandbach United v Barnton | Sandbach Community Football Centre | |
| 15:00 | Stockport Georgians v Stockport Town | Cromley Road | |
| Tuesday 27th December 2022 | Premier Division | ||
| 15:00 | Kendal Town v Longridge Town | Parkside Road Stadium | |
| Tuesday 27th December 2022 | First Division North | ||
| 15:00 | Ashton Town v Garstang | Hebs Group Stadium | |
| 15:00 | Ilkley Town v Steeton | MPM Stadium | |
| Tuesday 27th December 2022 | First Division South | ||
| 15:00 | New Mills v Abbey Hey | Church Lane | |
| Wednesday 28th December 2022 | Premier Division | ||
| 19:45 | Avro v FC Isle of Man | Vestacare Stadium | |
| Saturday 10th December 2022 The Macron Cup 3rd Round |
|
| Congleton Town v Lower Breck (13:00) | |
| Euxton Villa P-P FC St Helens (14:00) | |
| Postponed due to frozen pitch | |
| Northwich Victoria P-P Barnoldswick Town (14:00) | |
| Postponed due to frozen pitch | |
| South Liverpool v Abbey Hulton United (14:00) | |
| Squires Gate v Wythenshawe Town (14:00) | |
| Kendal Town P-P New Mills (15:00) | |
| Postponed due to frozen pitch | |
| Pilkington v Avro (15:00) | |
| Saturday 10th December 2022 The Edward Case Cup 3rd Round |
|
| Eccleshall P-P Abbey Hey (15:00) | |
| Postponed due to frozen pitch | |
| Saturday 10th December 2022 Premier Division |
|
| Winsford United P-P Bury AFC (13:30) | |
| Postponed due to frozen pitch | |
| FC Isle of Man v Litherland REMYCA (16:30) | |
| Saturday 10th December 2022 First Division North |
|
| Holker Old Boys P-P Atherton LR (12:45) | |
| Postponed due to frozen pitch | |
| Nelson P-P Garstang (13:00) | |
| Postponed due to frozen pitch | |
| Chadderton P-P Ashton Town (15:00) | |
| Postponed due to frozen pitch | |
| Ilkley Town v AFC Blackpool (15:00) | |
| Runcorn Town P-P Cleator Moor Celtic (15:00) | |
| Postponed due to frozen pitch | |
| Saturday 10th December 2022 First Division South |
|
| Brocton v Ellesmere Rangers (13:30) | |
| Alsager Town P-P Cheadle Town (14:00) | |
| Postponed due to frozen pitch | |
| Maine Road P-P Foley Meir (14:00) | |
| Postponed due to frozen pitch | |
| Rocester P-P Stockport Town (14:00) | |
| Postponed due to frozen pitch | |
| Stockport Georgians P-P Ashville (14:00) | |
| Postponed due to frozen pitch | |
| Wythenshawe Amateurs P-P Stafford Town (14:00) | |
| Postponed due to frozen pitch | |
| Saturday 10th December 2022 Wirral Senior Cup 2nd Round |
| Cammell Laird 1907 v Higher Bebington Kelma (14:00) |
| Sunday 11th December 2022 The Macron Cup 3rd Round |
| Barnton v Bacup Borough (15:00) |
| Monday 12th December 2022 First Division North |
| Daisy Hill v Euxton Villa (19:45) |
| Monday 12th December 2022 First Division South |
| Maine Road v Stockport Town (19:45) |
| Tuesday 13th December 2022 Premier Division |
| Bury AFC v Charnock Richard (19:45) |
| Longridge Town v Ashton Athletic (19:45) |
| Northwich Victoria v AFC Liverpool (19:45) |
| West Didsbury & Chorlton v Kendal Town (19:45) |
| Barnoldswick Town v Congleton Town (20:00) |
| Tuesday 13th December 2022 First Division North |
| Ashton Town v Pilkington (19:45) |
| Chadderton v FC St Helens (19:45) |
| Holker Old Boys v Ilkley Town (20:00) |
| Tuesday 13th December 2022 First Division South |
| Abbey Hulton United v Sandbach United (19:45) |
| Alsager Town v Eccleshall (19:45) |
| Cammell Laird 1907 v Barnton (19:45) |
| Cheadle Town v Foley Meir (19:45) |
| Stockport Georgians v Wythenshawe Amateurs (19:45) |
| Abbey Hey v Rocester (20:00) |
| Brocton v Ashville (20:00) |
| Wednesday 14th December 2022 Premier Division |
| Squires Gate v FC Isle of Man (20:00) |
| Wednesday 14th December 2022 First Division North |
| Bacup Borough v AFC Blackpool (20:00) |
| Friday 16th December 2022 Premier Division |
| Lower Breck v Padiham (20:00) |
| Saturday 17th December 2022 Premier Division |
| Irlam v Prestwich Heys (13:30) |
| Ashton Athletic v Squires Gate (14:00) |
| Burscough v Winsford United (15:00) |
| Congleton Town v Bury AFC (15:00) |
| Kendal Town v Avro (15:00) |
| Litherland REMYCA v Barnoldswick Town (15:00) |
| Longridge Town v Charnock Richard (15:00) |
| Vauxhall Motors v Northwich Victoria (15:00) |
| Wythenshawe Town v West Didsbury & Chorlton (15:00) |
| FC Isle of Man v AFC Liverpool (18:00) |
| Saturday 17th December 2022 First Division North |
| AFC Blackpool v Steeton (15:00) |
| Bacup Borough v Holker Old Boys (15:00) |
| Daisy Hill v Ashton Town (15:00) |
| Darwen FC v Chadderton (15:00) |
| Euxton Villa v Pilkington (15:00) |
| FC St Helens v Nelson (15:00) |
| Garstang v Atherton LR (15:00) |
| Runcorn Town v Ilkley Town (15:00) |
| South Liverpool v Cleator Moor Celtic (15:00) |
| Saturday 17th December 2022 First Division South |
| Alsager Town v Rocester (15:00) |
| Ashville v Eccleshall (15:00) |
| Barnton v Abbey Hulton United (15:00) |
| Brocton v Stockport Georgians (15:00) |
| Cheadle Heath Nomads v Wythenshawe Amateurs (15:00) |
| Ellesmere Rangers v Cheadle Town (15:00) |
| Foley Meir v Cammell Laird 1907 (15:00) |
| Maine Road v Abbey Hey (15:00) |
| New Mills v Stafford Town (15:00) |
| Stockport Town v Sandbach United (15:00) |
| Tuesday 20th December 2022 Premier Division |
| Burscough v Congleton Town (19:45) |
| Prestwich Heys v Longridge Town (19:45) |
| Squires Gate v Bury AFC (19:45) |
| Tuesday 20th December 2022 First Division North |
| Chadderton v Runcorn Town (19:45) |
| FC St Helens v Darwen FC (19:45) |
| Tuesday 20th December 2022 First Division South |
| Abbey Hulton United v Alsager Town (19:45) |
| New Mills v Brocton (19:45) |
| Eccleshall v Wythenshawe Amateurs (20:00) |
| Tuesday 20th December 2022 Lancashire Challenge Trophy 2nd Round |
| Charnock Richard v Padiham (19:45) |
| Wednesday 21st December 2022 Premier Division |
| Barnoldswick Town v Wythenshawe Town (19:45) |
| Northwich Victoria v Irlam (19:45) |
| Wednesday 21st December 2022 First Division North |
| Pilkington v Bacup Borough (19:45) |
| Saturday 24th December 2022 Premier Division |
| Northwich Victoria v Bury AFC (15:00) |
| Saturday 24th December 2022 First Division North |
| Cleator Moor Celtic v Bacup Borough (15:00) |
| Monday 26th December 2022 Premier Division |
| AFC Liverpool v Vauxhall Motors (13:30) |
| Northwich Victoria v Congleton Town (14:00) |
| Bury AFC v Wythenshawe Town (15:00) |
| Irlam v Ashton Athletic (15:00) |
| Padiham v Barnoldswick Town (15:00) |
| Prestwich Heys v Lower Breck (15:00) |
| Squires Gate v Burscough (15:00) |
| West Didsbury & Chorlton v Charnock Richard (15:00) |
| Winsford United v Litherland REMYCA (15:00) |
| Monday 26th December 2022 First Division North |
| Atherton LR v Daisy Hill (15:00) |
| Chadderton v Bacup Borough (15:00) |
| Cleator Moor Celtic v Holker Old Boys (15:00) |
| Darwen FC v Nelson (15:00) |
| Euxton Villa v AFC Blackpool (15:00) |
| Pilkington v FC St Helens (15:00) |
| Runcorn Town v South Liverpool (15:00) |
| Monday 26th December 2022 First Division South |
| Stafford Town v Brocton (12:00) |
| Cheadle Town v Cheadle Heath Nomads (12:30) |
| Wythenshawe Amateurs v Maine Road (14:00) |
| Cammell Laird 1907 v Ashville (15:00) |
| Eccleshall v Ellesmere Rangers (15:00) |
| Foley Meir v Alsager Town (15:00) |
| Rocester v Abbey Hulton United (15:00) |
| Sandbach United v Barnton (15:00) |
| Stockport Georgians v Stockport Town (15:00) |
| Tuesday 27th December 2022 Premier Division |
| Kendal Town v Longridge Town (15:00) |
| Tuesday 27th December 2022 First Division North |
| Ashton Town v Garstang (15:00) |
| Ilkley Town v Steeton (15:00) |
| Tuesday 27th December 2022 First Division South |
| New Mills v Abbey Hey (15:00) |
| Wednesday 28th December 2022 Premier Division |
| Avro v FC Isle of Man (19:45) |
