| Saturday 7th August 2010 | First Division | ||
|---|---|---|---|
| Leek CSOB | 0-0 | Atherton Collieries | Att: 0 |
| Wednesday 11th August 2010 | First Division | ||
|---|---|---|---|
| Eccleshall | 1-5 | Leek CSOB | Att: 5 |
| Saturday 14th August 2010 | F.A. Challenge Cup Extra Preliminary Round | ||
|---|---|---|---|
| Leek CSOB | 1-1 | Bootle | Att: 1 |
| Tuesday 17th August 2010 | F.A. Challenge Cup Extra Preliminary Round Replay | ||
|---|---|---|---|
| Bootle | 6-0 | Leek CSOB | Att: 0 |
| Saturday 21st August 2010 | First Division | ||
|---|---|---|---|
| AFC Darwen | 1-1 | Leek CSOB | Att: 1 |
| Saturday 4th September 2010 | F.A. Carlsberg Vase 1st Qualifying Round | ||
|---|---|---|---|
| Pershore Town | 2-1 | Leek CSOB | Att: 1 |
| Saturday 11th September 2010 | First Division | ||
|---|---|---|---|
| Irlam | 0-0 | Leek CSOB | Att: 0 |
| Saturday 18th September 2010 | First Division | ||
|---|---|---|---|
| Cheadle Town | 1-0 | Leek CSOB | Att: 0 |
| Saturday 25th September 2010 | First Division | ||
|---|---|---|---|
| Leek CSOB | 4-1 | Ashton Town | Att: 1 |
| Saturday 2nd October 2010 | First Division | ||
|---|---|---|---|
| Chadderton | 1-1 | Leek CSOB | Att: 1 |
| Saturday 9th October 2010 | Staffordshire F.A. Vase 1st Round | ||
|---|---|---|---|
| Wyrley | 1-2 | Leek CSOB | Att: 2 |
| Saturday 16th October 2010 | First Division | ||
|---|---|---|---|
| AFC Liverpool | 1-1 | Leek CSOB | Att: 1 |
| Tuesday 19th October 2010 | First Division | ||
|---|---|---|---|
| Norton United | 2-1 | Leek CSOB | Att: 1 |
| Saturday 23rd October 2010 | First Division | ||
|---|---|---|---|
| Daisy Hill | 5-1 | Leek CSOB | Att: 1 |
| Saturday 30th October 2010 | First Division | ||
|---|---|---|---|
| Leek CSOB | 1-1 | Cheadle Town | Att: 1 |
| Saturday 6th November 2010 | League Challenge Cup 2nd Round | ||
|---|---|---|---|
| Stone Dominoes | 3-2 | Leek CSOB | Att: 2 |
| Saturday 13th November 2010 | Staffordshire F.A. Vase 2nd Round | ||
|---|---|---|---|
| Florence | 0-4 | Leek CSOB | Att: 4 |
| Saturday 20th November 2010 | First Division | ||
|---|---|---|---|
| Leek CSOB | 1-4 | Chadderton | Att: 4 |
| Saturday 27th November 2010 | First Division Trophy 2nd Round | ||
|---|---|---|---|
| Ashton Town | 0-3 | Leek CSOB | Att: 3 |
| Saturday 8th January 2011 | Staffordshire F.A. Vase Quarter Finals | ||
|---|---|---|---|
| Wolverhampton Casuals | 1-1 | Leek CSOB | Att: 1 |
| (After Extra Time, 1-1 after 90 mins, Leek CSOB won 5-4 on penalties) | |||
| Saturday 15th January 2011 | First Division | ||
|---|---|---|---|
| Runcorn Town | 4-2 | Leek CSOB | Att: 2 |
| Saturday 5th February 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 2-1 | Leek CSOB | Att: 1 |
| Saturday 12th February 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 3-3 | AFC Darwen | Att: 3 |
| Saturday 19th February 2011 | First Division Trophy Quarter Finals | ||
|---|---|---|---|
| Atherton Collieries | 1-1 | Leek CSOB | Att: 1 |
| (After Extra Time, Atherton Collieries won 5-4 on penalties) | |||
| Tuesday 22nd February 2011 | First Division | ||
|---|---|---|---|
| Abbey Hey | 0-1 | Leek CSOB | Att: 1 |
| Tuesday 1st March 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 3-1 | Oldham Boro | |
| Saturday 5th March 2011 | First Division | ||
|---|---|---|---|
| Rochdale Town | 1-3 | Leek CSOB | Att: 3 |
| Tuesday 8th March 2011 | First Division | ||
|---|---|---|---|
| Ashton Town | 1-2 | Leek CSOB | Att: 2 |
| Saturday 12th March 2011 | Staffordshire F.A. Vase Semi Finals | ||
|---|---|---|---|
| Redgate Clayton | 0-3 | Leek CSOB | Att: 3 |
| Tuesday 15th March 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 0-1 | AFC Liverpool | Att: 1 |
| Saturday 19th March 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 2-1 | Irlam | Att: 1 |
| Tuesday 22nd March 2011 | First Division | ||
|---|---|---|---|
| Wigan Robin Park | 2-3 | Leek CSOB | Att: 3 |
| Saturday 26th March 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 1-2 | AFC Blackpool | Att: 2 |
| Saturday 2nd April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 3-2 | Rochdale Town | Att: 2 |
| Tuesday 5th April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 2-2 | Abbey Hey | Att: 2 |
| Thursday 7th April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 4-0 | Daisy Hill | Att: 0 |
| Saturday 9th April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 0-3 | Runcorn Town | Att: 3 |
| Monday 11th April 2011 | Staffordshire F.A. Vase Final | ||
|---|---|---|---|
| Leek CSOB | 2-2 | Norton United | Att: 2 |
| (After Extra Time, Leek CSOB won 5-3 on penalties) | |||
| Wednesday 13th April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 3-1 | Wigan Robin Park | Att: 1 |
| Saturday 16th April 2011 | First Division | ||
|---|---|---|---|
| Holker Old Boys | 3-0 | Leek CSOB | Att: 0 |
| Wednesday 20th April 2011 | First Division | ||
|---|---|---|---|
| Oldham Boro | 3-1 | Leek CSOB | Att: 1 |
| Saturday 23rd April 2011 | First Division | ||
|---|---|---|---|
| Atherton Collieries | 2-1 | Leek CSOB | Att: 1 |
| Monday 25th April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 1-2 | Norton United | Att: 2 |
| Wednesday 27th April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 1-1 | Eccleshall | Att: 1 |
| Saturday 30th April 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 1-3 | Holker Old Boys | Att: 3 |
