| Saturday 7th August 2010 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-0 | AFC Liverpool | Att: 0 |
| Tuesday 10th August 2010 | First Division | ||
|---|---|---|---|
| Holker Old Boys | 4-0 | Darwen FC | Att: 0 |
| Saturday 14th August 2010 | First Division | ||
|---|---|---|---|
| Runcorn Town | 4-0 | Darwen FC | Att: 0 |
| Saturday 21st August 2010 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-1 | Leek CSOB | Att: 1 |
| Saturday 28th August 2010 | First Division | ||
|---|---|---|---|
| Irlam | 1-0 | Darwen FC | Att: 0 |
| Saturday 4th September 2010 | First Division | ||
|---|---|---|---|
| Darwen FC | 0-0 | Oldham Boro | Att: 0 |
| Monday 6th September 2010 | First Division | ||
|---|---|---|---|
| Atherton Collieries | 7-0 | Darwen FC | Att: 0 |
| Saturday 11th September 2010 | First Division | ||
|---|---|---|---|
| Darwen FC | 2-1 | Wigan Robin Park | Att: 1 |
| Saturday 25th September 2010 | First Division | ||
|---|---|---|---|
| Norton United | 2-1 | Darwen FC | Att: 1 |
| Saturday 2nd October 2010 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-0 | Daisy Hill | Att: 0 |
| Tuesday 5th October 2010 | Lancashire Challenge Trophy 1st Round | ||
|---|---|---|---|
| Darwen FC | 1-3 | Chorley | Att: 3 |
| Saturday 9th October 2010 | League Challenge Cup 1st Round | ||
|---|---|---|---|
| Darwen FC | 1-0 | Ashton Town | Att: 0 |
| Saturday 16th October 2010 | First Division | ||
|---|---|---|---|
| Chadderton | 2-4 | Darwen FC | Att: 4 |
| Saturday 23rd October 2010 | First Division Trophy 1st Round | ||
|---|---|---|---|
| Darwen FC | 1-2 | Norton United | Att: 2 |
| Tuesday 26th October 2010 | First Division | ||
|---|---|---|---|
| Darwen FC | 0-3 | Holker Old Boys | Att: 3 |
| Saturday 30th October 2010 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 2-1 | Darwen FC | Att: 1 |
| Saturday 6th November 2010 | First Division | ||
|---|---|---|---|
| Ashton Town | 2-2 | Darwen FC | Att: 2 |
| Saturday 20th November 2010 | First Division | ||
|---|---|---|---|
| Daisy Hill | 1-1 | Darwen FC | Att: 1 |
| Saturday 8th January 2011 | First Division | ||
|---|---|---|---|
| Oldham Boro | 0-2 | Darwen FC | Att: 2 |
| Tuesday 8th February 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-2 | Atherton Collieries | Att: 2 |
| Saturday 12th February 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 3-3 | Darwen FC | Att: 3 |
| Thursday 17th February 2011 | League Challenge Cup 3rd Round | ||
|---|---|---|---|
| Glossop North End | 1-0 | Darwen FC | Att: 0 |
| Tuesday 1st March 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-6 | AFC Blackpool | Att: 6 |
| Saturday 5th March 2011 | First Division | ||
|---|---|---|---|
| Cheadle Town | 1-1 | Darwen FC | Att: 1 |
| Tuesday 8th March 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 3-1 | Rochdale Town | Att: 1 |
| Tuesday 15th March 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-1 | Abbey Hey | Att: 1 |
| Saturday 19th March 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 2-2 | Chadderton | Att: 2 |
| Saturday 26th March 2011 | First Division | ||
|---|---|---|---|
| Abbey Hey | 1-2 | Darwen FC | Att: 2 |
| Saturday 2nd April 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-1 | Eccleshall | Att: 1 |
| Monday 4th April 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-1 | Runcorn Town | Att: 1 |
| Wednesday 6th April 2011 | First Division | ||
|---|---|---|---|
| AFC Liverpool | 4-0 | Darwen FC | Att: 0 |
| Saturday 9th April 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 0-2 | Norton United | Att: 2 |
| Tuesday 12th April 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 3-1 | Ashton Town | Att: 1 |
| Saturday 16th April 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 2-1 | Irlam | Att: 1 |
| Tuesday 19th April 2011 | First Division | ||
|---|---|---|---|
| Wigan Robin Park | 5-0 | Darwen FC | Att: 0 |
| Saturday 23rd April 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 0-2 | Cheadle Town | Att: 2 |
| Monday 25th April 2011 | First Division | ||
|---|---|---|---|
| Rochdale Town | 2-1 | Darwen FC | Att: 1 |
| Saturday 30th April 2011 | First Division | ||
|---|---|---|---|
| Eccleshall | 3-0 | Darwen FC | Att: 0 |
