| Saturday 7th August 2010 | First Division | ||
|---|---|---|---|
| Irlam | 2-2 | AFC Blackpool | Att: 2 |
| Saturday 14th August 2010 | First Division | ||
|---|---|---|---|
| Rochdale Town | 2-4 | AFC Blackpool | Att: 4 |
| Saturday 21st August 2010 | First Division | ||
|---|---|---|---|
| Abbey Hey | 1-4 | AFC Blackpool | Att: 4 |
| Tuesday 24th August 2010 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 1-0 | Atherton Collieries | Att: 0 |
| Saturday 4th September 2010 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 1-2 | AFC Liverpool | Att: 2 |
| Saturday 11th September 2010 | First Division | ||
|---|---|---|---|
| Daisy Hill | 0-1 | AFC Blackpool | Att: 1 |
| Saturday 18th September 2010 | F.A. Carlsberg Vase 2nd Qualifying Round | ||
|---|---|---|---|
| AFC Blackpool | 3-2 | Squires Gate | Att: 2 |
| Saturday 25th September 2010 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 2-0 | Cheadle Town | Att: 0 |
| Saturday 2nd October 2010 | F.A. Carlsberg Vase 1st Round | ||
|---|---|---|---|
| Maine Road | 2-2 | AFC Blackpool | Att: 2 |
| (After Extra Time, 2-2 after 90 mins) | |||
| Tuesday 5th October 2010 | F.A. Carlsberg Vase 1st Round Replay | ||
|---|---|---|---|
| AFC Blackpool | 2-1 | Maine Road | Att: 1 |
| Saturday 9th October 2010 | League Challenge Cup 1st Round | ||
|---|---|---|---|
| AFC Blackpool | 2-0 | Rochdale Town | Att: 0 |
| Tuesday 12th October 2010 | Lancashire Challenge Trophy 1st Round | ||
|---|---|---|---|
| Bamber Bridge | 2-1 | AFC Blackpool | Att: 1 |
| Saturday 16th October 2010 | First Division | ||
|---|---|---|---|
| Eccleshall | 2-3 | AFC Blackpool | Att: 3 |
| Saturday 23rd October 2010 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 4-0 | Runcorn Town | Att: 0 |
| Saturday 30th October 2010 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 2-1 | Darwen FC | Att: 1 |
| Saturday 6th November 2010 | League Challenge Cup 2nd Round | ||
|---|---|---|---|
| Atherton Collieries | 0-2 | AFC Blackpool | Att: 2 |
| Saturday 13th November 2010 | F.A. Carlsberg Vase 2nd Round | ||
|---|---|---|---|
| AFC Blackpool | 0-2 | AFC Liverpool | Att: 2 |
| Saturday 20th November 2010 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 10-2 | Rochdale Town | Att: 2 |
| Monday 3rd January 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 2-1 | Wigan Robin Park | Att: 1 |
| Saturday 8th January 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 1-0 | Chadderton | Att: 0 |
| Saturday 15th January 2011 | First Division | ||
|---|---|---|---|
| Cheadle Town | 0-4 | AFC Blackpool | Att: 4 |
| Saturday 22nd January 2011 | First Division Trophy 2nd Round | ||
|---|---|---|---|
| AFC Blackpool | 4-0 | Holker Old Boys | Att: 0 |
| Saturday 5th February 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 2-1 | Leek CSOB | Att: 1 |
| Saturday 12th February 2011 | First Division | ||
|---|---|---|---|
| Wigan Robin Park | 1-4 | AFC Blackpool | Att: 4 |
| Tuesday 15th February 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 1-1 | Holker Old Boys | Att: 1 |
| Saturday 19th February 2011 | First Division | ||
|---|---|---|---|
| Chadderton | 3-2 | AFC Blackpool | Att: 2 |
| Tuesday 1st March 2011 | First Division | ||
|---|---|---|---|
| Darwen FC | 1-6 | AFC Blackpool | Att: 6 |
| Saturday 5th March 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 4-2 | Norton United | Att: 2 |
| Tuesday 8th March 2011 | League Challenge Cup 3rd Round | ||
|---|---|---|---|
| AFC Blackpool | 5-1 | St Helens Town | Att: 1 |
| Saturday 12th March 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 3-2 | Oldham Boro | Att: 2 |
| Saturday 19th March 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 4-0 | Daisy Hill | Att: 0 |
| Tuesday 22nd March 2011 | First Division | ||
|---|---|---|---|
| Ashton Town | 0-3 | AFC Blackpool | Att: 3 |
| Saturday 26th March 2011 | First Division | ||
|---|---|---|---|
| Leek CSOB | 1-2 | AFC Blackpool | Att: 2 |
| Tuesday 29th March 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 5-0 | Irlam | Att: 0 |
| Saturday 2nd April 2011 | First Division | ||
|---|---|---|---|
| Runcorn Town | 2-1 | AFC Blackpool | Att: 1 |
| Tuesday 5th April 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 3-1 | Ashton Town | Att: 1 |
| Saturday 9th April 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 3-1 | Eccleshall | Att: 1 |
| Tuesday 12th April 2011 | First Division Trophy Quarter Finals | ||
|---|---|---|---|
| AFC Blackpool | 3-1 | Runcorn Town | Att: 1 |
| Saturday 16th April 2011 | First Division | ||
|---|---|---|---|
| Norton United | 0-2 | AFC Blackpool | Att: 2 |
| Tuesday 19th April 2011 | First Division | ||
|---|---|---|---|
| AFC Blackpool | 1-0 | Abbey Hey | Att: 0 |
| Saturday 23rd April 2011 | First Division | ||
|---|---|---|---|
| Oldham Boro | 0-4 | AFC Blackpool | Att: 4 |
| Monday 25th April 2011 | First Division | ||
|---|---|---|---|
| Atherton Collieries | 0-0 | AFC Blackpool | Att: 0 |
| Wednesday 27th April 2011 | First Division | ||
|---|---|---|---|
| Holker Old Boys | 1-2 | AFC Blackpool | Att: 2 |
| Saturday 30th April 2011 | First Division | ||
|---|---|---|---|
| AFC Liverpool | 0-1 | AFC Blackpool | Att: 1 |
| Monday 2nd May 2011 | League Challenge Cup Quarter Finals | ||
|---|---|---|---|
| AFC Blackpool | 2-1 | Irlam | Att: 1 |
| Wednesday 4th May 2011 | First Division Trophy Semi Finals | ||
|---|---|---|---|
| AFC Blackpool | 1-2 | AFC Liverpool | Att: 2 |
| Saturday 7th May 2011 | League Challenge Cup Semi Finals | ||
|---|---|---|---|
| Winsford United | 2-1 | AFC Blackpool | Att: 1 |
