| Sat 26/07/25 | Runcorn Town v Market Drayton Town * | 4-0 | |  | | | | |
| Tue 29/07/25 | Ashville v Runcorn Town | 0-2 | | | | | | |
| Sat 02/08/25 | Haughmond v Runcorn Town | 2-4 | | | | | | |
| Sat 16/08/25 | Runcorn Town v Sandbach United | 1-2 | | | | | | |
| Wed 10/09/25 | Runcorn Town v Cammell Laird 1907 | 2-1 |  | | | | | |
| Sat 13/09/25 | Eccleshall v Runcorn Town | 2-2 | | | | | |  |
| Mon 15/09/25 | Cheadle Heath Nomads v Runcorn Town | 0-1 | | | |  | | |
| Sat 20/09/25 | Stockport Town v Runcorn Town (CUP) | 0-2 | | | | | | |
| Sat 27/09/25 | Runcorn Town v Barnton (CUP) | 1-0 | | | | | | |
| Sat 04/10/25 | Runcorn Town v Foley Meir * | 5-1 | | | | | | |
| Sat 11/10/25 | Runcorn Town v Allscott Heath (CUP) | 1-0 | | | | | | |
| Tue 14/10/25 | Alsager Town v Runcorn Town * | 0-4 | | | | | | |
| Sat 18/10/25 | Runcorn Town v Fulwood Amateurs (CUP) | 1-3 | | | | | | |
| Tue 21/10/25 | Runcorn Town v Ashville | 0-0 | | | | | | |
| Sat 01/11/25 | Telford Town v Runcorn Town * | 0-1 | | | | | | |
| Sat 08/11/25 | Runcorn Town v Stockport Georgians | 3-1 | | | | | | |
| Sat 15/11/25 | Runcorn Town v Stafford Town (CUP) | 2-1 | | | | | | |
| Sat 22/11/25 | Telford Town v Runcorn Town (CUP) | 4-0 | | | | | | |
| Tue 25/11/25 | Runcorn Town v Allscott Heath | 3-2 | | | | | | |
| Fri 26/12/25 | Barnton v Runcorn Town * | 0-2 | | | | | | |
| Sat 10/01/26 | Runcorn Town v Shawbury United * | 6-0 | | | | | | |
| Sat 17/01/26 | Market Drayton Town v Runcorn Town | 0-7 | | | | | | |
| Sat 31/01/26 | Sandbach United v Runcorn Town (CUP) | 1-2 | | | | | | |
| Tue 10/02/26 | Runcorn Town v Stafford Town * | 6-1 | | | | | | |
| Sat 21/02/26 | Sandbach United v Runcorn Town * | 0-2 | | | | | | |
| Thu 26/02/26 | Allscott Heath v Runcorn Town | 0-4 | | | | | | |
| Sat 28/02/26 | Runcorn Town v Telford Town | 12-0 | | | | | | |
| Sat 07/03/26 | Stafford Town v Runcorn Town * | 1-3 | | | | | | |
| Tue 10/03/26 | Wolverhampton Casuals v Runcorn Town * | 1-3 | | | | | | |
| Sat 14/03/26 | Nelson v Runcorn Town (CUP) | 0-2 | | | | | | |
| Tue 17/03/26 | Foley Meir v Runcorn Town | 1-5 | | | | | | |
| Mon 23/03/26 | Stockport Town v Runcorn Town (CUP) | 2-3 | | | | | | |
| Wed 25/03/26 | Cammell Laird 1907 v Runcorn Town | 0-3 | | | | | | |
| Sat 28/03/26 | Runcorn Town v Cheadle Heath Nomads * | 1-1 | | | | | | |
