| Sat 31/07/21 | Abbey Hey v Stockport Town | 2-2 | | | | | |
| Mon 02/08/21 | Stockport Town v West Didsbury & Chorlton * | 0-1 | | | | | |
| Sat 07/08/21 | Eccleshall v Stockport Town | 0-2 | | | | | |
| Sat 14/08/21 | Stockport Town v Wythenshawe Amateurs | 0-1 | | | | | |
| Mon 16/08/21 | Stockport Town v Cheadle Heath Nomads | 2-3 | | | | | |
| Sat 21/08/21 | Rocester v Stockport Town | 0-6 |  | | | | |
| Sat 28/08/21 | Stockport Town v Ellesmere Rangers | 1-4 | | | | | |
| Mon 30/08/21 | New Mills v Stockport Town | 4-2 | | |  | | |
| Sat 11/09/21 | Sandbach United v Stockport Town | 2-1 | | | | | |
| Sat 18/09/21 | Stockport Town v FC Isle of Man | 2-3 | | | | | |
| Sat 02/10/21 | Brocton v Stockport Town | 0-4 | | | | | |
| Sat 09/10/21 | Stockport Town v Alsager Town | 1-3 | | | |  | |
| Sat 23/10/21 | Stockport Town v Barnton | 1-1 | | | | | |
| Sat 30/10/21 | Cammell Laird 1907 v Stockport Town | 0-4 | | | | | |
| Sat 20/11/21 | West Didsbury & Chorlton v Stockport Town | 2-1 | | | | | |
| Sat 11/12/21 | St Martins v Stockport Town * | 1-7 | | | | | |
| Sat 18/12/21 | Stockport Town v Cheadle Town | 1-2 | | | | | |
| Mon 27/12/21 | Stockport Town v Brocton * | 1-1 | | | | | |
| Sat 22/01/22 | Stockport Town v New Mills | 2-2 | | | | | |
| Sat 29/01/22 | Stockport Town v Sandbach United | 3-1 | | | | | |
| Tue 01/02/22 | Cheadle Heath Nomads v Stockport Town | 0-7 | | | | | |
| Sat 05/02/22 | Wythenshawe Amateurs v Stockport Town | - | | | | | |
| Sat 12/02/22 | Ellesmere Rangers v Stockport Town | 1-3 | | | | | |
| Sat 19/02/22 | Stockport Town v Cammell Laird 1907 | 4-0 | | | | | |
| Sat 26/02/22 | Maine Road v Stockport Town | 2-1 | | | | | |
| Tue 01/03/22 | Alsager Town v Stockport Town | 2-1 | | | | | |
| Sat 05/03/22 | Stockport Town v Eccleshall | 0-0 | | | | | |
| Tue 08/03/22 | Wythenshawe Amateurs v Stockport Town | 3-0 | | | | | |
| Tue 15/03/22 | Cammell Laird 1907 v Stockport Town | 3-2 | | | | | |
| Sat 19/03/22 | Stockport Town v Rocester | 2-2 | | | | | |
| Sat 26/03/22 | FC Isle of Man v Stockport Town | 3-2 | | | | | |
| Sat 02/04/22 | Stockport Town v Abbey Hey | 1-2 | | | | | |
