| Tue 23/08/22 | Northwich Victoria v Lower Breck * | 2-0 | | | | | |
| Fri 26/08/22 | Northwich Victoria v Cheadle Town * | 3-4 | | | | | |
| Mon 29/08/22 | Irlam v Northwich Victoria | 1-2 | | |  | | |
| Sat 03/09/22 | Kendal Town v Northwich Victoria | 1-4 | | | | | |
| Wed 14/09/22 | Northwich Victoria v West Didsbury & Chorlton | 2-1 | | | | | |
| Sat 17/09/22 | Ashton Athletic v Northwich Victoria | 2-6 | | | | | |
| Sat 24/09/22 | Northwich Victoria v Burscough | 3-1 | | | | | |
| Wed 28/09/22 | Northwich Victoria v Litherland REMYCA * | 2-2 | | | | | |
| Sat 08/10/22 | Lower Breck v Northwich Victoria * | 1-3 |  | | | | |
| Sat 15/10/22 | Wythenshawe Town v Northwich Victoria | 3-0 | | | | | |
| Tue 18/10/22 | Charnock Richard v Northwich Victoria * | 1-3 | | | | | |
| Sat 29/10/22 | Northwich Victoria v Vauxhall Motors * | 0-2 | | | | | |
| Wed 02/11/22 | Northwich Victoria v Kendal Town * | 0-2 | | | | | |
| Sat 05/11/22 | FC Isle of Man v Northwich Victoria * | 1-3 | | | | | |
| Wed 16/11/22 | Northwich Victoria v Macclesfield * | 2-4 | | | | | |
| Sat 19/11/22 | Northwich Victoria v Cheadle Town * | 2-0 | | | | | |
| Wed 23/11/22 | Northwich Victoria v Charnock Richard * | 3-0 | | | | | |
| Wed 30/11/22 | Northwich Victoria v Squires Gate * | 5-1 | | | | | |
| Sat 03/12/22 | Prestwich Heys v Northwich Victoria | 2-2 | | | | | |
| Tue 20/12/22 | Northwich Victoria v Irlam * | 4-1 | | | | | |
| Mon 26/12/22 | Northwich Victoria v Congleton Town | 1-2 | | | | | |
| Fri 30/12/22 | Northwich Victoria v Bury AFC | 1-6 | | | | | |
| Wed 04/01/23 | Barnton v Northwich Victoria * | 1-6 | | | |  | |
| Sat 28/01/23 | Northwich Victoria v Prestwich Heys * | 1-0 | | | | | |
| Wed 01/02/23 | Northwich Victoria v AFC Liverpool * | 2-0 | | | | | |
| Sat 11/02/23 | Northwich Victoria v Winsford United * | 2-0 | | | | | |
| Tue 14/02/23 | West Didsbury & Chorlton v Northwich Victoria | 1-1 | | | | | |
| Sat 18/02/23 | Congleton Town v Northwich Victoria * | 1-0 | | | | | |
| Sat 25/02/23 | Northwich Victoria v Barnoldswick Town * | 2-0 | | | | | |
| Tue 28/02/23 | Barnoldswick Town v Northwich Victoria * | 0-1 | | | | | |
| Sat 04/03/23 | Bury AFC v Northwich Victoria * | 2-0 | | | | | |
| Wed 08/03/23 | Litherland REMYCA v Northwich Victoria * | 1-0 | | | | | |
| Sun 12/03/23 | Northwich Victoria v FC Isle of Man | 1-1 | | | | | |
| Wed 15/03/23 | Northwich Victoria v Longridge Town | 1-2 | | | | | |
