| Sat 26/07/25 | Runcorn Town v Market Drayton Town | 4-0 | |  | | | | |
| Tue 29/07/25 | Ashville v Runcorn Town | 0-2 | | | | | | |
| Sat 02/08/25 | Haughmond v Runcorn Town | 2-4 |  | | | | | |
| Sat 09/08/25 | Runcorn Town v Wolverhampton Sporting Community | 7-0 | | | | | | |
| Sat 16/08/25 | Runcorn Town v Sandbach United | 1-2 | | | |  | | |
| Sat 30/08/25 | Shawbury United v Runcorn Town | 0-2 | | | | | | |
| Sat 06/09/25 | Runcorn Town v New Mills | 2-2 | | | | | | |
| Wed 10/09/25 | Runcorn Town v Cammell Laird 1907 | 2-1 | | | | | | |
| Sat 13/09/25 | Eccleshall v Runcorn Town | 2-2 | | | | | | |
| Mon 15/09/25 | Cheadle Heath Nomads v Runcorn Town | 0-1 | | | | | | |
| Sat 20/09/25 | Stockport Town v Runcorn Town (CUP) | 0-2 | | | | | | |
| Sat 27/09/25 | Runcorn Town v Barnton (CUP) | 1-0 | | | | | | |
| Sat 04/10/25 | Runcorn Town v Foley Meir | 5-1 | | | | | | |
| Tue 07/10/25 | AFC Liverpool v Runcorn Town (CUP) | 3-3 | | | | | | |
| Sat 11/10/25 | Runcorn Town v Allscott Heath (CUP) | 1-0 | | | | | | |
| Tue 14/10/25 | Alsager Town v Runcorn Town | 0-4 | | | | | | |
| Sat 18/10/25 | Runcorn Town v Fulwood Amateurs (CUP) | 1-3 | | | | | | |
| Tue 21/10/25 | Runcorn Town v Ashville | 0-0 | | | | | | |
| Sat 25/10/25 | Runcorn Town v Wolverhampton Casuals | 4-0 | | | | | | |
| Tue 28/10/25 | Runcorn Town v Cammell Laird 1907 (CUP) | 1-1 | | | | | | |
| Sat 01/11/25 | Telford Town v Runcorn Town | 0-1 | | | | | | |
| Sat 08/11/25 | Runcorn Town v Stockport Georgians | 3-1 | | | | | | |
| Sat 15/11/25 | Runcorn Town v Stafford Town (CUP) | 2-1 | | | | | | |
| Sat 22/11/25 | Telford Town v Runcorn Town (CUP) | 4-0 | | | | | | |
| Tue 25/11/25 | Runcorn Town v Allscott Heath | 3-2 | | | | | | |
| Tue 02/12/25 | Wolverhampton Sporting Community v Runcorn Town | 2-4 | | | | | | |
