| Tue 02/08/22 | Congleton Town v Ashton Athletic * | 4-0 | | | | | |
| Sat 06/08/22 | Abbey Hey v Congleton Town * | 0-4 | | | | | |
| Sat 13/08/22 | Bury AFC v Congleton Town | 2-1 | | | | | |
| Sat 20/08/22 | Congleton Town v Bootle | 0-0 | | | | | |
| Tue 23/08/22 | Bootle v Congleton Town | 1-4 | | | | | |
| Sat 27/08/22 | Congleton Town v FC Isle of Man | 5-1 | | | | | |
| Mon 29/08/22 | Congleton Town v Charnock Richard | 1-0 | | |  | | |
| Sat 03/09/22 | Nantwich Town v Congleton Town | 0-2 | | | | | |
| Wed 07/09/22 | Avro v Congleton Town | 0-2 | | | | | |
| Tue 13/09/22 | Vauxhall Motors v Congleton Town | 2-0 | | | | | |
| Sat 17/09/22 | Newcastle Town v Congleton Town | 1-1 | | | | | |
| Tue 20/09/22 | Congleton Town v Newcastle Town | 3-2 | | | | | |
| Sat 24/09/22 | Winsford United v Congleton Town | 0-2 | | | | | |
| Tue 27/09/22 | Irlam v Congleton Town | 3-0 | | | | | |
| Sat 01/10/22 | Congleton Town v AFC Fylde | 1-1 | | | | | |
| Tue 04/10/22 | AFC Fylde v Congleton Town | 5-1 | | | | | |
| Sat 08/10/22 | West Didsbury & Chorlton v Congleton Town * | 3-2 | | | | | |
| Tue 11/10/22 | Congleton Town v Burscough | 2-0 | | | | | |
| Sat 15/10/22 | Ellesmere Rangers v Congleton Town | 1-2 | | | | | |
| Tue 18/10/22 | Wythenshawe Town v Congleton Town | 2-1 |  | | | | |
| Sat 22/10/22 | Congleton Town v Lower Breck | 2-1 | | | | | |
| Tue 25/10/22 | Congleton Town v Prestwich Heys | 1-0 | | | | | |
| Sat 29/10/22 | FC Isle of Man v Congleton Town | 3-2 | | | | | |
| Tue 01/11/22 | Congleton Town v Barnton | 3-1 | | | | | |
| Sat 05/11/22 | Congleton Town v Litherland REMYCA | 2-1 | | | | | |
| Tue 08/11/22 | Congleton Town v AFC Liverpool | 2-0 | | | | |  |
| Sat 12/11/22 | Congleton Town v Coventry United | 2-1 | | | | | |
| Tue 15/11/22 | Congleton Town v Winsford United | 3-2 | | | | | |
| Sat 19/11/22 | Brocton v Congleton Town | 1-2 | | | | | |
| Sat 26/11/22 | Kendal Town v Congleton Town | 2-1 | | | | | |
| Sat 03/12/22 | Congleton Town v Lye Town | 4-3 | | | | | |
| Tue 06/12/22 | Congleton Town v Squires Gate | 2-1 | | | | | |
| Tue 20/12/22 | Burscough v Congleton Town | 1-2 | | | | | |
| Mon 26/12/22 | Northwich Victoria v Congleton Town | 1-2 | | | | | |
| Tue 03/01/23 | Congleton Town v Stockport Town | 3-0 | | | | | |
| Sat 14/01/23 | Congleton Town v Pinchbeck United | 4-0 | | | | | |
| Tue 24/01/23 | Congleton Town v Padiham | 1-2 | | | | | |
| Sat 28/01/23 | Congleton Town v Avro | 0-0 | | | | | |
| Wed 01/02/23 | Squires Gate v Congleton Town | 1-1 | | | | | |
| Sat 04/02/23 | Congleton Town v Irlam | 1-1 | | | | | |
| Tue 14/02/23 | Congleton Town v Bury AFC | 1-1 | | | | | |
| Sat 18/02/23 | Congleton Town v Northwich Victoria | 1-0 | | | | | |
| Tue 21/02/23 | Prestwich Heys v Congleton Town | 3-2 | | | | | |
| Sat 25/02/23 | Congleton Town v Vauxhall Motors | 2-0 | | | | | |
| Tue 28/02/23 | Congleton Town v Stalybridge Celtic | 1-0 | | | | | |
| Sat 04/03/23 | Ashton Athletic v Congleton Town | 1-3 | | | | | |
| Tue 07/03/23 | Congleton Town v Kendal Town * | 3-1 | | | | | |
| Sat 11/03/23 | Congleton Town v Bury AFC | 1-1 | | | | | |
| Thu 16/03/23 | Lower Breck v Congleton Town | 1-2 | | | | | |
| Sat 18/03/23 | Padiham v Congleton Town | 1-1 | | | | | |
| Thu 23/03/23 | Congleton Town v Barnoldswick Town | 1-0 | | | | | |
