| Sat 30/07/22 | South Liverpool v Daisy Hill | 2-4 | | |  | | |
| Wed 10/08/22 | South Liverpool v Chadderton | 2-3 | | | | | |
| Sat 20/08/22 | Cleator Moor Celtic v South Liverpool | 1-8 | | | | | |
| Mon 29/08/22 | Pilkington v South Liverpool | 3-1 | | | | | |
| Sat 03/09/22 | South Liverpool v Steeton | 1-3 | | | | | |
| Sat 17/09/22 | Garstang v South Liverpool | 3-4 | | | | | |
| Sat 24/09/22 | South Liverpool v Hallam | 1-2 | | | | | |
| Sat 01/10/22 | South Liverpool v Ilkley Town | 0-4 | | | | | |
| Tue 04/10/22 | FC St Helens v South Liverpool | 2-1 | | | | |  |
| Sat 08/10/22 | South Liverpool v Holker Old Boys | 1-1 | | | | | |
| Sat 15/10/22 | Vauxhall Motors v South Liverpool | 1-1 | | | | | |
| Sat 22/10/22 | Nelson v South Liverpool | 1-4 | | | | | |
| Sat 29/10/22 | South Liverpool v Holker Old Boys | 1-2 | | | | | |
| Wed 02/11/22 | South Liverpool v Skelmersdale United | 3-3 | | | | | |
| Sat 05/11/22 | South Liverpool v AFC Blackpool | 5-1 | | | | | |
| Sat 12/11/22 | Atherton LR v South Liverpool | 1-3 | | | | | |
| Wed 28/12/22 | South Liverpool v Runcorn Town | 5-0 | | | | | |
| Sat 07/01/23 | South Liverpool v Darwen FC | 1-4 | | | |  | |
| Sat 04/02/23 | Ashton Town v South Liverpool | 0-0 | | | | | |
| Fri 10/02/23 | South Liverpool v Pilkington | 1-2 | | | | | |
| Sat 18/02/23 | South Liverpool v Bacup Borough | 2-4 | | | | | |
| Sat 25/02/23 | South Liverpool v Abbey Hulton United | 1-1 | | | | | |
| Wed 01/03/23 | South Liverpool v Bacup Borough | 4-1 | | | | | |
| Sat 04/03/23 | Daisy Hill v South Liverpool | 0-4 | | | | | |
| Tue 07/03/23 | AFC Blackpool v South Liverpool | 2-0 | | | | | |
| Sat 18/03/23 | South Liverpool v Garstang | 4-2 | | | | | |
| Sat 25/03/23 | Chadderton v South Liverpool | 2-1 | | | | | |
| Wed 29/03/23 | South Liverpool v FC St Helens | 1-2 | | | | | |
| Fri 31/03/23 | Euxton Villa v South Liverpool | 1-1 | | | | | |
| Mon 03/04/23 | Bacup Borough v South Liverpool | 1-2 | | | | | |
| Wed 05/04/23 | Runcorn Town v South Liverpool | 2-1 | | | | | |
| Sat 08/04/23 | South Liverpool v Cleator Moor Celtic * | 2-0 | | | | | |
| Mon 10/04/23 | Holker Old Boys v South Liverpool | 2-3 | | | | | |
| Sat 15/04/23 | Ilkley Town v South Liverpool | 3-2 | | | | | |
