| Tue 23/08/22 | Ashton Athletic v AFC Liverpool * | 1-2 | | | | | |
| Mon 29/08/22 | AFC Liverpool v FC Isle of Man | 5-2 | | | | | |
| Sat 03/09/22 | Prestwich Heys v AFC Liverpool | 0-2 | | | | | |
| Wed 07/09/22 | AFC Liverpool v Winsford United | 1-2 | | | | | |
| Wed 21/09/22 | AFC Liverpool v Litherland REMYCA | 1-0 | | | | | |
| Sat 24/09/22 | AFC Liverpool v Bury AFC | 1-0 | | | | | |
| Sun 16/10/22 | AFC Liverpool v FC Isle of Man * | 1-0 | | | | | |
| Thu 20/10/22 | Lower Breck v AFC Liverpool * | 2-0 | | | | | |
| Sat 22/10/22 | Winsford United v AFC Liverpool | 1-1 | | | | | |
| Sat 29/10/22 | AFC Liverpool v Avro | 1-0 | | | | | |
| Sat 05/11/22 | AFC Liverpool v Wythenshawe Town | 1-3 | | | | | |
| Tue 08/11/22 | Congleton Town v AFC Liverpool | 2-0 | | | | | |
| Sun 13/11/22 | AFC Liverpool v FC St Helens | 1-1 | | | | | |
| Wed 16/11/22 | AFC Liverpool v Lower Breck | 0-0 | | | | | |
| Sat 19/11/22 | Wythenshawe Town v AFC Liverpool | 5-1 | | | | | |
| Sat 26/11/22 | Litherland REMYCA v AFC Liverpool | 0-0 | | | | | |
| Wed 30/11/22 | AFC Liverpool v Lower Breck | 4-3 | | | | | |
| Sat 03/12/22 | AFC Liverpool v Cheadle Town | 2-1 | | | | | |
| Mon 26/12/22 | AFC Liverpool v Vauxhall Motors | 4-2 | | | | | |
| Wed 18/01/23 | AFC Liverpool v Kendal Town * | 5-0 | | | | | |
| Wed 01/02/23 | Northwich Victoria v AFC Liverpool * | 2-0 | | | | | |
| Sat 04/02/23 | AFC Liverpool v Charnock Richard | 1-3 | | | | | |
| Wed 08/02/23 | AFC Liverpool v Longridge Town | 3-2 | | | | | |
| Sat 11/02/23 | AFC Liverpool v Ashton Athletic | 0-2 | | | | | |
| Tue 14/02/23 | Southport v AFC Liverpool | 1-0 | | | | | |
| Sat 18/02/23 | West Didsbury & Chorlton v AFC Liverpool | 3-0 | | | | | |
| Sat 25/02/23 | Kendal Town v AFC Liverpool | 3-1 | | | | | |
| Fri 10/03/23 | AFC Liverpool v Squires Gate * | 2-0 | | | | | |
| Sat 18/03/23 | Wythenshawe Town v AFC Liverpool | 4-0 | | | | | |
| Sat 25/03/23 | AFC Liverpool v Burscough | 1-1 | | | | | |
| Thu 30/03/23 | Bury AFC v AFC Liverpool | 2-1 | | | | | |
| Sat 01/04/23 | Padiham v AFC Liverpool | 2-2 | | | | | |
| Mon 10/04/23 | Vauxhall Motors v AFC Liverpool | 4-1 | | | | | |
| Wed 19/04/23 | AFC Liverpool v Congleton Town | 8-2 | | | | | |
| Sat 22/04/23 | Irlam v AFC Liverpool | 2-0 | | | | | |
