| Sat 31/07/21 | Barnton v Wythenshawe Amateurs | 1-2 | | | | | |
| Sat 07/08/21 | Abbey Hulton United v Barnton | 3-1 | | | | | |
| Sat 14/08/21 | Barnton v Ellesmere Rangers | 2-3 | | | | | |
| Tue 17/08/21 | West Didsbury & Chorlton v Barnton | 6-0 | | |  | | |
| Sat 21/08/21 | Barnton v New Mills | 2-5 | | | | | |
| Fri 27/08/21 | Barnton v Eccleshall | 5-1 | | | | | |
| Mon 30/08/21 | Alsager Town v Barnton | 0-1 | | | | | |
| Wed 08/09/21 | Barnton v Abbey Hey | 1-2 | | | | | |
| Sat 11/09/21 | Dronfield Town v Barnton | 1-0 | | | | | |
| Sat 18/09/21 | Rocester v Barnton | 0-1 | | | | | |
| Sat 25/09/21 | Barnton v Brocton | 4-2 | | | | | |
| Sat 02/10/21 | Cheadle Heath Nomads v Barnton | 3-1 | | | | | |
| Wed 13/10/21 | Barnton v FC Isle of Man | 1-6 | | | | | |
| Sat 16/10/21 | Cheadle Town v Barnton | 3-0 | | | | | |
| Wed 20/10/21 | Barnton v 1874 Northwich | 2-0 | | | | | |
| Sat 23/10/21 | Stockport Town v Barnton | 1-1 | | | | | |
| Sat 30/10/21 | Barnton v St Martins | 5-1 | | | | | |
| Sat 06/11/21 | Sandbach United v Barnton | 1-1 | | | | |  |
| Wed 10/11/21 | Barnton v Maine Road | 0-4 | | | | | |
| Sat 13/11/21 | Barnton v Cammell Laird 1907 | 1-2 | | | | | |
| Sat 20/11/21 | Barnton v Alsager Town | 1-2 | | | | | |
| Sat 27/11/21 | Ellesmere Rangers v Barnton | 0-2 | | | | | |
| Sat 04/12/21 | Cammell Laird 1907 v Barnton | 1-1 | | | | | |
| Sat 18/12/21 | New Mills v Barnton | 2-2 | | | | | |
| Mon 27/12/21 | Barnton v Sandbach United | 2-2 | | | | | |
| Wed 12/01/22 | Barnton v Abbey Hulton United | 5-2 | | | | | |
| Sat 15/01/22 | Wythenshawe Amateurs v Barnton | 1-1 | | | | | |
| Tue 18/01/22 | Stalybridge Celtic v Barnton | 4-1 | | | | | |
| Sat 22/01/22 | Barnton v Rocester | 4-1 | | | | | |
| Sat 29/01/22 | FC Isle of Man v Barnton | 4-0 | | | | | |
| Sat 05/02/22 | Barnton v Stafford Town | 1-2 | | | | | |
| Sat 12/02/22 | Barnton v Cheadle Heath Nomads | 1-1 | | | | | |
| Tue 15/02/22 | Winsford United v Barnton | 2-0 | | | | | |
| Sat 26/02/22 | Eccleshall v Barnton | 2-0 | | | | | |
| Sat 05/03/22 | Barnton v Cheadle Town | 0-2 | | | | | |
| Tue 08/03/22 | Abbey Hey v Barnton | 5-0 | | | | | |
| Sat 12/03/22 | Barnton v Stockport Town | 2-0 | | | | | |
| Sat 19/03/22 | Brocton v Barnton | 1-2 | | | | | |
| Wed 23/03/22 | Barnton v West Didsbury & Chorlton | 1-2 | | | | | |
| Sat 26/03/22 | St Martins v Barnton | 0-5 | | | | | |
| Wed 30/03/22 | Barnton v Irlam | 2-1 | | | | | |
| Sat 02/04/22 | Maine Road v Barnton | 2-1 | | | | | |
| Wed 06/04/22 | Barnton v Cammell Laird 1907 | 1-2 | | | | | |
| Wed 13/04/22 | Barnton v South Liverpool | 4-4 | | | | | |
| Sat 30/04/22 | Cammell Laird 1907 v Barnton | 1-0 | | | | | |
