| Sat 30/07/22 | Abbey Hulton United v Cheadle Town | 1-1 | | | | | |
| Sat 06/08/22 | Cammell Laird 1907 v Cheadle Town | 1-3 | | | | | |
| Tue 09/08/22 | Cheadle Town v Stockport Town | 1-3 | | |  | | |
| Sat 13/08/22 | Stafford Town v Cheadle Town | 2-5 | | | | | |
| Tue 16/08/22 | Cheadle Town v Ellesmere Rangers * | 1-2 | | | | | |
| Sat 20/08/22 | Cheadle Town v Wythenshawe Amateurs | 3-2 | | | | | |
| Fri 26/08/22 | Northwich Victoria v Cheadle Town | 3-4 |  | | | | |
| Mon 29/08/22 | Abbey Hey v Cheadle Town | 0-2 | | | | | |
| Sat 03/09/22 | Cheadle Town v Barnton * | 1-1 | | | | | |
| Tue 06/09/22 | Ashville v Cheadle Town | 0-2 | | | | | |
| Sat 17/09/22 | Cheadle Town v Sandbach United | 4-3 | | | | | |
| Sat 24/09/22 | Cheadle Town v Maltby Main | 3-2 | | | | | |
| Sat 01/10/22 | Cheadle Town v Rocester * | 7-2 | | | | | |
| Sat 08/10/22 | Sandbach United v Cheadle Town | 3-4 | | | | | |
| Sat 15/10/22 | Cheadle Town v Rocester | 6-1 | | | | | |
| Sat 22/10/22 | Barton Town v Cheadle Town * | 2-4 | | | | | |
| Wed 26/10/22 | Foley Meir v Cheadle Town | 1-3 | | | | | |
| Sat 29/10/22 | Wythenshawe Amateurs v Cheadle Town | 2-0 | | | | | |
| Sat 05/11/22 | Cheadle Town v Stafford Town | 1-0 | | | | | |
| Tue 08/11/22 | Stockport Georgians v Cheadle Town | 0-2 | | | | | |
| Sat 12/11/22 | Brigg Town v Cheadle Town | 0-3 | | | | | |
| Tue 15/11/22 | Sandbach United v Cheadle Town | 4-0 | | | | | |
| Sat 19/11/22 | Northwich Victoria v Cheadle Town | 2-0 | | | | | |
| Sat 26/11/22 | Cheadle Town v Ellesmere Rangers | 1-2 | | | | | |
| Wed 30/11/22 | Brocton v Cheadle Town | 6-2 | | | | | |
| Sat 03/12/22 | AFC Liverpool v Cheadle Town | 2-1 | | | | | |
| Mon 26/12/22 | Cheadle Town v Cheadle Heath Nomads | 2-4 | | | | | |
| Sat 07/01/23 | Cheadle Town v Ashville | 3-0 | | | | | |
| Tue 24/01/23 | Cheadle Town v Foley Meir | 12-0 | | | | | |
| Sat 28/01/23 | Stockport Town v Cheadle Town | 1-1 | | | | | |
| Tue 31/01/23 | Ellesmere Rangers v Cheadle Town | 0-0 | | | | | |
| Sat 04/02/23 | Cheadle Town v Abbey Hey | 4-2 | | | | | |
| Mon 06/02/23 | Maine Road v Cheadle Town | 1-3 | | | | | |
| Sat 11/02/23 | Cheadle Town v Cammell Laird 1907 | 2-0 | | | | | |
| Sat 18/02/23 | New Mills v Cheadle Town | 4-2 | | | | | |
| Tue 21/02/23 | Alsager Town v Cheadle Town | 2-0 | | | | | |
| Tue 07/03/23 | Cheadle Town v Eccleshall * | 1-3 | | | | | |
| Sat 11/03/23 | Cheadle Town v Alsager Town | 3-0 | | | | | |
| Tue 14/03/23 | Cheadle Town v Stockport Georgians | 1-0 | | | | | |
| Tue 21/03/23 | Cheadle Town v Brocton | 5-2 | | | | | |
