| Sat 26/07/25 | Euxton Villa v Prestwich Heys | 1-1 | | | |  | | |
| Tue 29/07/25 | Euxton Villa v Longridge Town | 1-1 | | | | | | |
| Sat 09/08/25 | West Didsbury & Chorlton v Euxton Villa | 3-3 | | | | | | |
| Tue 12/08/25 | Padiham v Euxton Villa | 2-0 | | | | | | |
| Sat 16/08/25 | Euxton Villa v Barnoldswick Town | 2-3 | | | | | | |
| Sat 23/08/25 | Euxton Villa v Worsbrough Bridge Athletic (CUP) | 2-1 |  | | | | | |
| Mon 25/08/25 | Euxton Villa v Litherland REMYCA | 3-2 | | | | | | |
| Sat 30/08/25 | Stockport Town v Euxton Villa | 1-1 | | | | | | |
| Tue 16/09/25 | Chadderton v Euxton Villa | 2-2 | | | | | | |
| Sat 20/09/25 | Euxton Villa v Sandbach United (CUP) | 3-3 | | | | | | |
| Tue 23/09/25 | Euxton Villa v Ramsbottom United | 0-4 | | | | | | |
| Fri 26/09/25 | Euxton Villa v Holker Old Boys (CUP) | 5-0 | |  | | | | |
| Sat 04/10/25 | Abbey Hey v Euxton Villa * | 1-2 | | | | | | |
| Sat 11/10/25 | Colne v Euxton Villa (CUP) | 1-3 | | | | | | |
| Wed 15/10/25 | South Liverpool v Euxton Villa | 1-1 | | | | | | |
| Tue 04/11/25 | Euxton Villa v FC Isle of Man * | 3-3 | | | | | | |
| Sat 08/11/25 | Longridge Town v Euxton Villa * | 4-3 | | | | | | |
| Tue 11/11/25 | Euxton Villa v AFC Liverpool | 0-3 | | | | | | |
| Sat 15/11/25 | Wythenshawe v Euxton Villa * | 2-0 | | | | | | |
| Fri 21/11/25 | Euxton Villa v Charnock Richard (CUP) | 3-3 | | | | | | |
| Sat 29/11/25 | Euxton Villa v Glossop North End | 3-2 | | | | | | |
| Sat 06/12/25 | Pilkington v Euxton Villa | - | | | | | | |
| Sat 20/12/25 | Euxton Villa v Atherton LR | - | | | | | | |
| Fri 26/12/25 | Euxton Villa v Charnock Richard | 2-1 | | | | | | |
| Wed 14/01/26 | Litherland REMYCA v Euxton Villa | 1-3 | | | | | | |
| Sat 17/01/26 | Euxton Villa v Wythenshawe | 0-3 | | | | | | |
| Wed 21/01/26 | Pilkington v Euxton Villa | 0-3 | | | | | | |
| Sat 24/01/26 | Euxton Villa v Pilkington | 1-1 | | | | | | |
| Sat 31/01/26 | Euxton Villa v Abbey Hey | 5-4 | | | | | | |
