| Sat 26/07/25 | Euxton Villa v Prestwich Heys * | 1-1 | | | | | | |
| Tue 29/07/25 | Euxton Villa v Longridge Town * | 1-1 | | | | | | |
| Sat 09/08/25 | West Didsbury & Chorlton v Euxton Villa * | 3-3 | | | | | | |
| Tue 12/08/25 | Padiham v Euxton Villa | 2-0 | | | |  | | |
| Sat 23/08/25 | Euxton Villa v Worsbrough Bridge Athletic (CUP) | 2-1 | | | | | | |
| Mon 25/08/25 | Euxton Villa v Litherland REMYCA * | 3-2 | | | | | | |
| Sat 30/08/25 | Stockport Town v Euxton Villa * | 1-1 | | | | | | |
| Fri 05/09/25 | Euxton Villa v FC St Helens * | 1-2 | | | | | | |
| Tue 09/09/25 | Euxton Villa v Burscough * | 0-1 | | | | | | |
| Tue 16/09/25 | Chadderton v Euxton Villa * | 2-2 | | | | | | |
| Sat 20/09/25 | Euxton Villa v Sandbach United (CUP) * | 3-3 | | | | | | |
| Fri 26/09/25 | Euxton Villa v Holker Old Boys (CUP) | 5-0 |  |  | | | | |
| Sat 04/10/25 | Abbey Hey v Euxton Villa | 1-2 | | | | | | |
| Sat 11/10/25 | Colne v Euxton Villa (CUP) | 1-3 | | | | | | |
| Sat 18/10/25 | Euxton Villa v Carlisle City (CUP) | 1-1 | | | | | | |
| Sat 25/10/25 | Euxton Villa v Cheadle Town | 1-1 | | | | | | |
| Sat 01/11/25 | City of Liverpool v Euxton Villa | 0-0 | | | | | | |
| Tue 04/11/25 | Euxton Villa v FC Isle of Man | 3-3 | | | | | | |
| Sat 08/11/25 | Longridge Town v Euxton Villa * | 4-3 | | | | | | |
| Tue 11/11/25 | Euxton Villa v AFC Liverpool * | 0-3 | | | | | | |
| Sat 15/11/25 | Wythenshawe v Euxton Villa * | 2-0 | | | | | | |
| Fri 21/11/25 | Euxton Villa v Charnock Richard (CUP) | 3-3 | | | | | | |
| Sat 29/11/25 | Euxton Villa v Glossop North End * | 3-2 | | | | | | |
| Fri 26/12/25 | Euxton Villa v Charnock Richard * | 2-1 | | | | | | |
| Wed 14/01/26 | Litherland REMYCA v Euxton Villa * | 1-3 | | | | | | |
| Sat 17/01/26 | Euxton Villa v Wythenshawe | 0-3 | | | | | | |
| Sat 24/01/26 | Euxton Villa v Pilkington * | 1-1 | | | | | | |
