| Wed 30/07/25 | Litherland REMYCA v City of Liverpool | 2-0 | |  | | | | |
| Sat 02/08/25 | Whitchurch Alport v Litherland REMYCA (CUP) | 3-0 | | | | | | |
| Sat 09/08/25 | Litherland REMYCA v Barnoldswick Town * | 1-3 | | | | | | |
| Wed 13/08/25 | South Liverpool v Litherland REMYCA | 2-1 | | | | | | |
| Sat 16/08/25 | Burscough v Litherland REMYCA | 3-0 | | | | |  | |
| Sat 06/09/25 | Stockport Town v Litherland REMYCA | 1-0 | | | | | | |
| Tue 09/09/25 | Longridge Town v Litherland REMYCA | 3-0 | | | | | | |
| Sat 13/09/25 | Litherland REMYCA v Glossop North End | 1-2 | | | |  | | |
| Tue 16/09/25 | Atherton LR v Litherland REMYCA | 3-1 | | | | | | |
| Sat 20/09/25 | Litherland REMYCA v South Liverpool | 0-3 | | | | | | |
| Wed 24/09/25 | Pilkington v Litherland REMYCA | 1-0 | | | | | | |
| Sat 24/01/26 | Irlam v Litherland REMYCA * | 4-0 | | | | | | |
| Wed 28/01/26 | Litherland REMYCA v FC St Helens * | 2-2 | | | | | | |
| Sat 14/02/26 | Chadderton v Litherland REMYCA * | 2-0 | | | | | | |
| Tue 03/03/26 | Ramsbottom United v Litherland REMYCA * | 1-1 | | | | | | |
| Sat 07/03/26 | Prestwich Heys v Litherland REMYCA * | 2-1 | | | | | | |
| Sat 14/03/26 | Litherland REMYCA v Charnock Richard * | 2-5 | | | | | | |
| Sat 21/03/26 | City of Liverpool v Litherland REMYCA | 0-4 | | | | | | |
| Tue 24/03/26 | Cheadle Town v Litherland REMYCA | 0-3 | | | | | | |
| Sat 28/03/26 | Litherland REMYCA v Abbey Hey | 2-2 | | | | | | |
| Tue 31/03/26 | Wythenshawe v Litherland REMYCA | 1-2 | | | | | | |
| Sat 04/04/26 | Litherland REMYCA v Ramsbottom United | 2-1 | | | | | | |
| Mon 06/04/26 | AFC Liverpool v Litherland REMYCA | 3-1 | | | | | | |
| Sat 11/04/26 | Litherland REMYCA v Atherton LR | 0-4 | | | | | | |
