| Sat 23/08/25 | Euxton Villa v Worsbrough Bridge Athletic (CUP) | 2-1 | | | |  | | |
| Mon 25/08/25 | Euxton Villa v Litherland REMYCA | 3-2 | | | | | | |
| Sat 30/08/25 | Stockport Town v Euxton Villa * | 1-1 | | | | | | |
| Fri 05/09/25 | Euxton Villa v FC St Helens * | 1-2 | | | | | | |
| Sat 20/09/25 | Euxton Villa v Sandbach United (CUP) | 3-3 | | | | | | |
| Fri 26/09/25 | Euxton Villa v Holker Old Boys (CUP) | 5-0 | |  | | | | |
| Sat 04/10/25 | Abbey Hey v Euxton Villa * | 1-2 | | | | | | |
| Sat 11/10/25 | Colne v Euxton Villa (CUP) | 1-3 | | | | | | |
| Tue 21/10/25 | Burscough v Euxton Villa * | 3-0 | | | | | | |
| Sat 25/10/25 | Euxton Villa v Cheadle Town | 1-1 | | | | | | |
| Fri 26/12/25 | Euxton Villa v Charnock Richard | 2-1 | | | | | | |
| Sat 17/01/26 | Euxton Villa v Wythenshawe | 0-3 | | | | | | |
| Wed 21/01/26 | Pilkington v Euxton Villa * | 0-3 | | | | | | |
| Sat 24/01/26 | Euxton Villa v Pilkington * | 1-1 | | | | | | |
| Sat 31/01/26 | Euxton Villa v Abbey Hey * | 5-4 | | | | | | |
| Sat 07/02/26 | FC Isle of Man v Euxton Villa * | 1-0 | | | | | | |
| Tue 10/02/26 | Prestwich Heys v Euxton Villa | 3-1 | | | | | | |
| Tue 17/02/26 | AFC Liverpool v Euxton Villa (CUP) | 3-0 | | | | | | |
| Tue 24/02/26 | Ramsbottom United v Euxton Villa | 0-1 | | | | | | |
| Tue 03/03/26 | FC St Helens v Euxton Villa | 0-0 | | | | | | |
| Sat 07/03/26 | Euxton Villa v Stockport Town | 1-4 | | | | | | |
| Tue 10/03/26 | Euxton Villa v Chadderton | 0-1 | | | | | | |
| Sat 14/03/26 | Euxton Villa v Padiham * | 2-1 | | | | | | |
| Tue 17/03/26 | Cheadle Town v Euxton Villa | 1-1 | | | | | | |
| Sat 21/03/26 | Irlam v Euxton Villa | 1-1 | | | | | | |
| Tue 24/03/26 | Euxton Villa v Atherton LR | 0-5 | | | | | | |
