| Sat 22/11/25 | Cheadle Town v Chadderton (CUP) * | 2-1 | | | | | | |
| Tue 25/11/25 | Cheadle Town v Longridge Town * | 2-2 | | | | | | |
| Sat 29/11/25 | AFC Liverpool v Cheadle Town | 2-2 | | | | | | |
| Wed 03/12/25 | Litherland REMYCA v Cheadle Town * | 4-2 | | | | | | |
| Sat 06/12/25 | Padiham v Cheadle Town | 1-4 | | | | | | |
| Fri 12/12/25 | Cheadle Town v Stockport Town | 1-2 | | | | | | |
| Wed 17/12/25 | South Liverpool v Cheadle Town | 2-2 | | | |  | | |
| Sat 27/12/25 | Cheadle Town v Abbey Hey | 3-1 | | | | | | |
| Tue 13/01/26 | Irlam v Cheadle Town * | 6-0 | | | | | | |
| Thu 15/01/26 | Cheadle Town v Sandbach United (CUP) | 1-1 | | | | | | |
| Sat 17/01/26 | Cheadle Town v Burscough * | 0-0 | |  | | | | |
| Tue 20/01/26 | Cheadle Town v Chadderton * | 1-2 | | | | | | |
| Sat 14/02/26 | Burscough v Cheadle Town (CUP) | 4-0 | | | | | | |
| Sat 21/02/26 | Cheadle Town v Pilkington | 2-0 | | | | | | |
| Sat 28/02/26 | City of Liverpool v Cheadle Town | 2-2 | | | | | | |
| Tue 03/03/26 | Longridge Town v Cheadle Town | 2-0 | | | | | | |
| Sat 07/03/26 | Cheadle Town v Charnock Richard | 1-0 | | | | | | |
| Sat 14/03/26 | Barnoldswick Town v Cheadle Town | 3-1 | | | | | | |
| Tue 17/03/26 | Cheadle Town v Euxton Villa * | 1-1 | | | | | | |
| Sat 21/03/26 | FC Isle of Man v Cheadle Town | 1-2 | | | | | | |
| Tue 24/03/26 | Cheadle Town v Litherland REMYCA | 0-3 | | | | | | |
| Sat 28/03/26 | Cheadle Town v Wythenshawe | 0-1 | | | | | | |
| Mon 06/04/26 | Abbey Hey v Cheadle Town | 1-1 | | | | | | |
| Sat 11/04/26 | Cheadle Town v Padiham | 2-3 | | | | | | |
| Mon 13/04/26 | West Didsbury & Chorlton v Cheadle Town | 1-2 | | | | | | |
| Sat 18/04/26 | Cheadle Town v Prestwich Heys | 0-3 | | | | | | |
