| Friday 21st November 2025 | The Macron Cup 3rd Rnd | ||
| 19:45 |  Euxton Villa v Charnock Richard  | Jim Fowler Memorial Ground | |
| 19:45 |  MSB Woolton v Thornton Cleveleys  | Jericho Lane | |
| Saturday 22nd November 2025 | The Macron Cup 3rd Rnd | ||
| 15:00 |  Burscough v AFC Blackpool  | The Community Ground | |
| 15:00 |  Cammell Laird 1907 v AFC Liverpool  | The OWS Engineering Ltd Stadium | |
| 15:00 |  Cheadle Town v Chadderton  | The Ground Up Solutions Stadium | |
| 15:00 |  Ramsbottom United v West Didsbury & Chorlton  | Harry Williams Riverside Stadium | |
| 15:00 |  Sandbach United v Nelson  | Sandbach Community Football Centre | |
| 15:00 |  Telford Town v Runcorn Town  | DRM Aggregate Arena | |
| Friday 21st November 2025 The Macron Cup 3rd Round |
| Euxton Villa v Charnock Richard (19:45) |
| MSB Woolton v Thornton Cleveleys (19:45) |
| Saturday 22nd November 2025 The Macron Cup 3rd Round |
| Burscough v AFC Blackpool (15:00) |
| Cammell Laird 1907 v AFC Liverpool (15:00) |
| Cheadle Town v Chadderton (15:00) |
| Ramsbottom United v West Didsbury & Chorlton (15:00) |
| Sandbach United v Nelson (15:00) |
| Telford Town v Runcorn Town (15:00) |
