| Friday 31st March 2023 First Division North |
||
| Euxton Villa | 1-1 | South Liverpool |
| Thursday 30th March 2023 West Riding County Cup Semi Finals |
||
| Liversedge | 3-1 | Barnoldswick Town |
| Thursday 30th March 2023 Premier Division |
||
| Bury AFC | 2-1 | AFC Liverpool |
| Wednesday 29th March 2023 Lancashire Challenge Trophy Semi Finals |
||
| Ashton Athletic | 0-9 | Southport |
| Wednesday 29th March 2023 Premier Division |
||
| Northwich Victoria | 3-2 | Padiham |
| Wednesday 29th March 2023 First Division North |
||
| Bacup Borough | P-P | Pilkington |
| Postponed due to Waterlogged Pitch | ||
| South Liverpool | 1-2 | FC St Helens |
| Wednesday 29th March 2023 First Division South |
||
| Barnton | 0-3 | Cheadle Town |
| Tuesday 28th March 2023 Premier Division |
||
| Charnock Richard | P-P | Congleton Town |
| Postponed due to to help Congleton Town FA Vase preparation | ||
| Prestwich Heys | P-P | West Didsbury & Chorlton |
| Postponed due to waterlogged pitch | ||
| Vauxhall Motors | 2-1 | Bury AFC |
| Tuesday 28th March 2023 First Division North |
||
| Holker Old Boys | P-P | Cleator Moor Celtic |
| Postponed due to waterlogged pitch | ||
| Ilkley Town | 3-4 | Chadderton |
| Steeton | 3-2 | Garstang |
| Tuesday 28th March 2023 First Division South |
||
| Abbey Hulton United | 1-2 | Eccleshall |
| Ashville | 2-0 | Rocester |
| Brocton | 1-2 | Wythenshawe Amateurs |
| Foley Meir | P-P | Sandbach United |
| Postponed due to waterlogged pitch | ||
| New Mills | 4-1 | Ellesmere Rangers |
| Monday 27th March 2023 First Division North |
||
| Runcorn Town | 3-1 | Bacup Borough |
| Monday 27th March 2023 First Division South |
||
| Maine Road | 2-2 | Cheadle Heath Nomads |
| Saturday 25th March 2023 Premier Division |
||
| AFC Liverpool | 1-1 | Burscough |
| Ashton Athletic | 2-6 | Charnock Richard |
| Barnoldswick Town | P-P | Longridge Town |
| Postponed due to waterlogged pitch | ||
| Bury AFC | 1-1 | Kendal Town |
| FC Isle of Man | 2-2 | West Didsbury & Chorlton |
| Litherland REMYCA | 1-0 | Congleton Town |
| Squires Gate | 5-2 | Prestwich Heys |
| Vauxhall Motors | 1-0 | Irlam |
| Winsford United | 2-0 | Padiham |
| Wythenshawe Town | 2-0 | Lower Breck |
| Saturday 25th March 2023 First Division North |
||
| Ashton Town | 2-1 | Runcorn Town |
| Chadderton | 2-1 | South Liverpool |
| Cleator Moor Celtic | 0-2 | Pilkington |
| Daisy Hill | 0-1 | Bacup Borough |
| Darwen FC | 2-1 | Atherton LR |
| Euxton Villa | P-P | Steeton |
| Postponed due to waterlogged pitch | ||
| FC St Helens | 3-1 | Holker Old Boys |
| Nelson | P-P | Ilkley Town |
| Postponed due to waterlogged pitch | ||
| Saturday 25th March 2023 First Division South |
||
| Alsager Town | 1-2 | Barnton |
| Cammell Laird 1907 | 2-2 | Abbey Hulton United |
| Cheadle Town | 0-1 | New Mills |
| Eccleshall | 1-0 | Stockport Georgians |
| Ellesmere Rangers | 3-1 | Ashville |
| Foley Meir | P-P | Sandbach United |
| Postponed due to waterlogged pitch | ||
| Maine Road | 1-2 | Brocton |
| Stafford Town | 4-3 | Rocester |
| Stockport Town | 1-1 | Cheadle Heath Nomads |
| Wythenshawe Amateurs | 2-0 | Abbey Hey |
| Sat 1st Apr 2023 The Isuzu FA Vase Semi Finals |
|||
| 15:00 | Congleton Town v Newport Pagnell Town | ||
| The Edward Case Cup Semi Finals | |||
| 15:00 | Bacup Borough v Abbey Hulton United | ||
| Premier Division | |||
| 15:00 | Ashton Athletic v Burscough | ||
| 15:00 | Avro v Winsford United | ||
| 15:00 | Charnock Richard v Bury AFC | ||
| 15:00 | Irlam v Litherland REMYCA | ||
| 15:00 | Kendal Town v West Didsbury & Chorlton | ||
| 15:00 | Longridge Town v Northwich Victoria | ||
| 15:00 | Lower Breck v FC Isle of Man | ||
| 15:00 | Padiham v AFC Liverpool | ||
| 15:00 | Prestwich Heys v Barnoldswick Town | ||
| 15:00 | Squires Gate v Vauxhall Motors | ||
| First Division North | |||
| 15:00 | Atherton LR v AFC Blackpool | ||
| 15:00 | Chadderton v Nelson | ||
| 15:00 | Cleator Moor Celtic v Ashton Town | ||
| 15:00 | Darwen FC v Daisy Hill | ||
| 15:00 | Ilkley Town v FC St Helens | ||
| 15:00 | Pilkington v Garstang | ||
| 15:00 | Steeton v Holker Old Boys | ||
| First Division South | |||
| 15:00 | Ashville v Alsager Town | ||
| 15:00 | Barnton v Ellesmere Rangers | ||
| 15:00 | Foley Meir v Cheadle Heath Nomads | ||
| 15:00 | New Mills v Cammell Laird 1907 | ||
| 15:00 | Rocester v Brocton | ||
| 15:00 | Sandbach United v Stockport Town | ||
| 15:00 | Stafford Town v Maine Road | ||
| 15:00 | Stockport Georgians v Abbey Hey | ||
| 15:00 | Wythenshawe Amateurs v Eccleshall | ||
Saturday KO 15:00, Midweek KO 19:45 unless stated
| Sunday 2nd April 2023 Premier Division |
| Longridge Town v FC Isle of Man (13:45) |
| Monday 3rd April 2023 First Division North |
| Bacup Borough v South Liverpool (20:00) |
| Tuesday 4th April 2023 Premier Division |
| Bury AFC v Vauxhall Motors |
| Played at Mossley |
| Charnock Richard v Winsford United |
| Padiham v Kendal Town |
| Prestwich Heys v Wythenshawe Town |
| West Didsbury & Chorlton v Avro |
| Barnoldswick Town v Congleton Town (20:00) |
| Tuesday 4th April 2023 First Division North |
| Euxton Villa v Steeton |
| Cleator Moor Celtic v Nelson (20:00) |
| Holker Old Boys v Chadderton (20:00) |
| Tuesday 4th April 2023 First Division South |
| Cheadle Town v Abbey Hulton United |
| Ashville v Foley Meir (20:00) |
| Wednesday 5th April 2023 First Division North |
| Runcorn Town v South Liverpool |
| Bacup Borough v Ashton Town (20:00) |
| Thursday 6th April 2023 First Division North |
| Nelson v Ilkley Town |
| Friday 7th April 2023 Premier Division |
| Bury AFC v Longridge Town |
| Saturday 8th April 2023 The Macron Cup Semi Finals |
| Bacup Borough v FC St Helens |
| Kendal Town v Congleton Town |
| Saturday 8th April 2023 The Edward Case Cup Semi Finals |
| Chadderton v Ellesmere Rangers |
| Saturday 8th April 2023 Premier Division |
| Winsford United v Vauxhall Motors |
| FC Isle of Man v Avro (18:30) |
| Saturday 8th April 2023 First Division North |
| Holker Old Boys v Daisy Hill |
| Nelson v Ashton Town |
| South Liverpool v Cleator Moor Celtic |
| Saturday 8th April 2023 First Division South |
| Ashville v Cammell Laird 1907 |
| Monday 10th April 2023 Premier Division |
| Ashton Athletic v Irlam |
| Barnoldswick Town v Padiham |
| Burscough v Squires Gate |
| Charnock Richard v West Didsbury & Chorlton |
| Congleton Town v Northwich Victoria |
| Longridge Town v Kendal Town |
| Lower Breck v Prestwich Heys |
| Vauxhall Motors v AFC Liverpool |
| Winsford United v Litherland REMYCA |
| Wythenshawe Town v Bury AFC |
| Monday 10th April 2023 First Division North |
| AFC Blackpool v Euxton Villa |
| Bacup Borough v Chadderton |
| Daisy Hill v Atherton LR |
| FC St Helens v Pilkington |
| Garstang v Ashton Town |
| Holker Old Boys v South Liverpool |
| Nelson v Darwen FC |
| Runcorn Town v Cleator Moor Celtic |
| Steeton v Ilkley Town |
| Monday 10th April 2023 First Division South |
| Cheadle Heath Nomads v Cheadle Town (12:30) |
| Abbey Hey v New Mills |
| Abbey Hulton United v Rocester |
| Alsager Town v Foley Meir |
| Barnton v Sandbach United |
| Brocton v Stafford Town |
| Ellesmere Rangers v Eccleshall |
| Maine Road v Wythenshawe Amateurs |
| Stockport Town v Stockport Georgians |
| Premier Division | P | GD | Pts | |
| 1 | Vauxhall Motors | 36 | 39 | 79 |
| 2 | Avro | 37 | 38 | 79 |
| 3 | Wythenshawe Town | 38 | 53 | 78 |
| 4 | Bury AFC | 34 | 30 | 72 |
| 5 | Northwich Victoria | 38 | 22 | 69 |
| 6 | AFC Liverpool | 38 | 19 | 63 |
| 7 | Congleton Town | 36 | 18 | 63 |
| 8 | Prestwich Heys | 37 | 13 | 63 |
| 9 | West Didsbury & Chorlton | 34 | 23 | 58 |
| 10 | Charnock Richard | 36 | 1 | 49 |
| 11 | Litherland REMYCA | 37 | -9 | 47 |
| 12 | Padiham | 37 | -4 | 45 |
| 13 | Kendal Town | 37 | -14 | 45 |
| 14 | Longridge Town | 35 | -18 | 45 |
| 15 | Lower Breck | 37 | -8 | 43 |
| 16 | Winsford United | 36 | -14 | 42 |
| 17 | Squires Gate | 38 | -26 | 41 |
| 18 | Irlam | 38 | -11 | 37 |
| 19 | FC Isle of Man | 37 | -31 | 37 |
| 20 | Barnoldswick Town | 35 | -19 | 36 |
| 21 | Burscough | 37 | -42 | 27 |
| 22 | Ashton Athletic | 38 | -60 | 18 |
| First Division North | P | GD | Pts | |
| 1 | Pilkington | 30 | 47 | 71 |
| 2 | Chadderton | 30 | 30 | 69 |
| 3 | FC St Helens | 31 | 25 | 57 |
| 4 | Euxton Villa | 31 | 27 | 56 |
| 5 | Ilkley Town | 30 | 18 | 53 |
| 6 | Steeton | 30 | 10 | 47 |
| 7 | Holker Old Boys | 28 | 9 | 47 |
| 8 | Darwen FC | 31 | 7 | 44 |
| 9 | AFC Blackpool | 31 | -1 | 44 |
| 10 | Bacup Borough | 27 | 2 | 38 |
| 11 | South Liverpool | 29 | 9 | 37 |
| 12 | Atherton LR | 31 | -12 | 35 |
| 13 | Daisy Hill | 30 | -18 | 32 |
| 14 | Garstang | 30 | -14 | 31 |
| 15 | Ashton Town | 29 | -30 | 30 |
| 16 | Nelson | 27 | -13 | 27 |
| 17 | Runcorn Town | 31 | -51 | 23 |
| 18 | Cleator Moor Celtic | 28 | -45 | 15 |
| First Division South | P | GD | Pts | |
| 1 | Wythenshawe Amateurs | 35 | 52 | 87 |
| 2 | Stockport Town | 35 | 73 | 86 |
| 3 | Brocton | 35 | 24 | 72 |
| 4 | Sandbach United | 34 | 28 | 67 |
| 5 | Cheadle Town | 35 | 29 | 64 |
| 6 | Ellesmere Rangers | 35 | 26 | 60 |
| 7 | New Mills | 35 | 20 | 57 |
| 8 | Stockport Georgians | 35 | 8 | 51 |
| 9 | Eccleshall | 35 | -4 | 51 |
| 10 | Cheadle Heath Nomads | 35 | 12 | 48 |
| 11 | Barnton | 35 | -2 | 48 |
| 12 | Maine Road | 35 | -4 | 47 |
| 13 | Ashville | 34 | -2 | 46 |
| 14 | Abbey Hulton United | 35 | 6 | 44 |
| 15 | Abbey Hey | 35 | -14 | 42 |
| 16 | Cammell Laird 1907 | 35 | -29 | 33 |
| 17 | Alsager Town | 35 | -18 | 32 |
| 18 | Stafford Town | 35 | -54 | 27 |
| 19 | Foley Meir | 33 | -63 | 18 |
| 20 | Rocester | 35 | -88 | 8 |
Tables correct as at Fri 31st Mar 2023
