| Wednesday 26th November 2025 Manchester Premier Cup 1st Round |
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| West Didsbury & Chorlton | 3-1 | Stalybridge Celtic |
| Wednesday 26th November 2025 The Edward Case Cup 2nd Round South |
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| Telford Town | 3-0 | Stockport Georgians |
| Wednesday 26th November 2025 Premier Division |
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| Litherland REMYCA | 0-2 | Prestwich Heys |
| Wednesday 26th November 2025 First Division North |
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| MSB Woolton | 0-1 | Steeton |
| Tuesday 25th November 2025 Lancashire Challenge Trophy 2nd Round |
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| Bamber Bridge | 2-1 | Thornton Cleveleys |
| Tuesday 25th November 2025 Manchester Premier Cup 1st Round |
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| FC United of Manchester | 1-1 | Abbey Hey |
| (Abbey Hey won 5-4 on penalties) | ||
| Wythenshawe Town | 5-3 | Glossop North End |
| Tuesday 25th November 2025 Premier Division |
||
| Atherton LR | 1-4 | Irlam |
| Chadderton | 3-3 | Ramsbottom United |
| Cheadle Town | 2-2 | Longridge Town |
| Wythenshawe | 3-1 | South Liverpool |
| Tuesday 25th November 2025 First Division South |
||
| Alsager Town | 0-1 | Barnton |
| Runcorn Town | 3-2 | Allscott Heath |
| Stafford Town | 2-2 | Sandbach United |
| Tuesday 25th November 2025 Cheshire Senior Cup 2nd Round |
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| Ashville | 0-4 | Crewe Alexandra |
| Monday 24th November 2025 Manchester Premier Cup 1st Round |
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| Maine Road | 2-4 | Bury |
| Saturday 22nd November 2025 The Macron Cup 3rd Round |
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| Burscough | 3-1 | AFC Blackpool |
| Cheadle Town | 2-1 | Chadderton |
| Ramsbottom United | 1-2 | West Didsbury & Chorlton |
| Sandbach United | 1-3 | Nelson |
| Telford Town | 4-0 | Runcorn Town |
| Saturday 22nd November 2025 Premier Division |
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| Abbey Hey | 1-2 | Atherton LR |
| Barnoldswick Town | 1-1 | FC St Helens |
| Litherland REMYCA | 0-6 | Stockport Town |
| Longridge Town | 2-5 | FC Isle of Man |
| Pilkington | 1-10 | Padiham |
| Prestwich Heys | 0-2 | Glossop North End |
| South Liverpool | 0-3 | Irlam |
| Wythenshawe | 11-1 | City of Liverpool |
| Saturday 22nd November 2025 First Division North |
||
| Ashton Town | 2-0 | Fulwood Amateurs |
| Bacup Borough | P-P | Squires Gate |
| Postponed due to Frozen Pitch | ||
| Garstang | P-P | Colne |
| Postponed due to Waterlogged Pitch | ||
| Maghull | 1-1 | Darwen FC |
| Maine Road | 2-4 | Daisy Hill |
| Saturday 22nd November 2025 First Division South |
||
| Alsager Town | 2-3 | Cheadle Heath Nomads |
| Ashville | 4-1 | Shawbury United |
| Barnton | 0-3 | Eccleshall |
| Haughmond | 1-2 | Cammell Laird 1907 |
| New Mills | 1-3 | Foley Meir |
| Wolverhampton Sporting Community | 1-3 | Market Drayton Town |
Saturday KO 15:00, Midweek KO 19:45 unless stated
| Friday 28th November 2025 Premier Division |
| FC St Helens v Litherland REMYCA |
| Saturday 29th November 2025 Premier Division |
| Prestwich Heys v FC Isle of Man (14:00) |
| AFC Liverpool v Cheadle Town |
| Atherton LR v Abbey Hey |
| Barnoldswick Town v City of Liverpool |
| Burscough v Padiham |
| Euxton Villa v Glossop North End |
| Ramsbottom United v Irlam |
| South Liverpool v Chadderton |
| Stockport Town v Longridge Town |
| West Didsbury & Chorlton v Charnock Richard |
| Wythenshawe v Pilkington |
| Saturday 29th November 2025 First Division North |
| AFC Blackpool v Colne |
| Ashton Athletic v Steeton |
| Daisy Hill v Thornton Cleveleys |
| Darwen FC v Ashton Town |
| Droylsden v Fulwood Amateurs |
| Garstang v Maine Road |
| Holker Old Boys v Squires Gate |
| Nelson v Maghull |
| Saturday 29th November 2025 First Division South |
| Allscott Heath v New Mills |
| Cammell Laird 1907 v Wolverhampton Sporting Community |
| Eccleshall v Haughmond |
| Foley Meir v Cheadle Heath Nomads |
| Market Drayton Town v Barnton |
| Sandbach United v Stockport Georgians |
| Shawbury United v Telford Town |
| Stafford Town v Alsager Town |
| Wolverhampton Casuals v Runcorn Town |
| Premier Division | P | GD | Pts | |
| 1 | Ramsbottom United | 21 | 40 | 51 |
| 2 | Padiham | 21 | 36 | 50 |
| 3 | West Didsbury & Chorlton | 22 | 28 | 49 |
| 4 | Wythenshawe | 20 | 24 | 46 |
| 5 | Irlam | 20 | 19 | 40 |
| 6 | FC St Helens | 22 | 13 | 37 |
| 7 | Burscough | 20 | 13 | 35 |
| 8 | Chadderton | 18 | 26 | 33 |
| 9 | South Liverpool | 21 | 0 | 33 |
| 10 | Stockport Town | 22 | 3 | 31 |
| 11 | Atherton LR | 20 | 9 | 30 |
| 12 | Longridge Town | 21 | -1 | 29 |
| 13 | Glossop North End | 24 | -12 | 29 |
| 14 | Pilkington | 22 | -27 | 26 |
| 15 | Prestwich Heys | 19 | -3 | 24 |
| 16 | Charnock Richard | 19 | 6 | 23 |
| 17 | Cheadle Town | 18 | -4 | 22 |
| 18 | Barnoldswick Town | 19 | -17 | 22 |
| 19 | FC Isle of Man | 23 | -24 | 20 |
| 20 | AFC Liverpool | 19 | -8 | 19 |
| 21 | Euxton Villa | 21 | -15 | 18 |
| 22 | City of Liverpool | 21 | -43 | 16 |
| 23 | Abbey Hey | 20 | -23 | 12 |
| 24 | Litherland REMYCA | 21 | -40 | 4 |
| First Division North | P | GD | Pts | |
| 1 | Ashton Town | 14 | 4 | 26 |
| 2 | Maghull | 14 | 12 | 25 |
| 3 | Darwen FC | 14 | 5 | 22 |
| 4 | Nelson | 9 | 1 | 21 |
| 5 | Bacup Borough | 13 | -1 | 21 |
| 6 | Droylsden | 13 | 8 | 20 |
| 7 | AFC Blackpool | 11 | 7 | 20 |
| 8 | Daisy Hill | 15 | 0 | 20 |
| 9 | Holker Old Boys | 10 | 10 | 19 |
| 10 | Fulwood Amateurs | 12 | 3 | 18 |
| 11 | Thornton Cleveleys | 13 | 4 | 17 |
| 12 | Colne | 13 | -1 | 16 |
| 13 | Steeton | 15 | -7 | 16 |
| 14 | Squires Gate | 14 | -6 | 15 |
| 15 | Maine Road | 14 | 2 | 14 |
| 16 | MSB Woolton | 13 | -7 | 14 |
| 17 | Ashton Athletic | 13 | -13 | 10 |
| 18 | Garstang | 12 | -21 | 8 |
| First Division South | P | GD | Pts | |
| 1 | Runcorn Town | 17 | 34 | 42 |
| 2 | Eccleshall | 16 | 16 | 36 |
| 3 | Barnton | 18 | 10 | 32 |
| 4 | Telford Town | 15 | 17 | 30 |
| 5 | Sandbach United | 17 | 10 | 30 |
| 6 | Stockport Georgians | 16 | 12 | 29 |
| 7 | Stafford Town | 15 | 18 | 28 |
| 8 | Foley Meir | 18 | 3 | 28 |
| 9 | New Mills | 16 | 12 | 26 |
| 10 | Ashville | 16 | 8 | 25 |
| 11 | Allscott Heath | 17 | 7 | 23 |
| 12 | Cheadle Heath Nomads | 18 | -2 | 21 |
| 13 | Market Drayton Town | 19 | -11 | 18 |
| 14 | Cammell Laird 1907 | 16 | -13 | 18 |
| 15 | Alsager Town | 18 | -7 | 17 |
| 16 | Wolverhampton Casuals | 15 | -8 | 17 |
| 17 | Shawbury United | 18 | -33 | 14 |
| 18 | Haughmond | 18 | -30 | 9 |
| 19 | Wolverhampton Sporting Community | 17 | -43 | 5 |
Tables correct as at Tue 25th Nov 2025
