| Saturday 8th March 2025 First Division North |
||
| Ashton Athletic | 2-1 | Bacup Borough |
| Ashton Town | 2-0 | Steeton |
| Droylsden | 1-2 | Daisy Hill |
| Garstang | 0-4 | Euxton Villa |
| Holker Old Boys | 3-1 | Atherton LR |
| Maghull | 4-0 | AFC Blackpool |
| Saturday 8th March 2025 First Division South |
||
| Ashville | 1-2 | Stockport Georgians |
| Barnton | 3-1 | New Mills |
| Eccleshall | 0-1 | Cammell Laird 1907 |
| Foley Meir | 1-4 | Market Drayton Town |
| Runcorn Town | 1-0 | Abbey Hulton United |
| Stafford Town | A-A | Alsager Town |
| Abandoned due to Match abandoned on 90 minutes due to player injury. Score was 2-0. | ||
| Tue 11th Mar 2025 Staffordshire Senior Cup Quarter Finals |
|||
| 19:45 | Stafford Town v Chasetown | ||
| Premier Division | |||
| 19:45 | Charnock Richard v Glossop North End | ||
Saturday KO 15:00, Midweek KO 19:45 unless stated
| Wednesday 12th March 2025 Lancashire Challenge Trophy Semi Finals |
| Bacup Borough v Padiham (20:00) |
| Wednesday 12th March 2025 First Division North |
| AFC Blackpool v Ashton Athletic |
| Thursday 13th March 2025 Premier Division |
| Lower Breck v South Liverpool (20:00) |
| Friday 14th March 2025 First Division South |
| Winsford United v Shawbury United (20:00) |
| Saturday 15th March 2025 The Edward Case Cup Semi Finals |
| Holker Old Boys v Atherton LR |
| Stafford Town v Ashville |
| Saturday 15th March 2025 Premier Division |
| AFC Liverpool v Lower Breck |
| Barnoldswick Town v Abbey Hey |
| Burscough v Colne |
| Cheadle Town v Charnock Richard |
| FC Isle of Man v Pilkington |
| FC St Helens v Bury |
| Irlam v Longridge Town |
| Ramsbottom United v Litherland REMYCA |
| South Liverpool v Glossop North End |
| West Didsbury & Chorlton v Padiham |
| Saturday 15th March 2025 First Division North |
| Daisy Hill v AFC Blackpool |
| Saturday 15th March 2025 First Division South |
| Cammell Laird 1907 v Barnton |
| Foley Meir v Stockport Georgians |
| Sunday 16th March 2025 Premier Division |
| FC Isle of Man v Prestwich Heys (11:00) |
| Premier Division | P | GD | Pts | |
| 1 | Bury | 40 | 66 | 91 |
| 2 | Lower Breck | 38 | 50 | 82 |
| 3 | Ramsbottom United | 39 | 41 | 81 |
| 4 | Padiham | 39 | 31 | 76 |
| 5 | West Didsbury & Chorlton | 40 | 34 | 73 |
| 6 | Irlam * | 40 | 24 | 69 |
| 7 | Chadderton | 41 | 12 | 67 |
| 8 | FC St Helens | 40 | 7 | 61 |
| 9 | Stockport Town | 41 | -1 | 61 |
| 10 | Cheadle Town | 40 | 8 | 58 |
| 11 | FC Isle of Man | 39 | 5 | 58 |
| 12 | AFC Liverpool | 40 | -1 | 58 |
| 13 | Abbey Hey | 40 | -5 | 58 |
| 14 | Barnoldswick Town | 40 | -8 | 54 |
| 15 | Charnock Richard | 40 | 4 | 53 |
| 16 | Burscough | 39 | -11 | 51 |
| 17 | Glossop North End | 40 | -11 | 48 |
| 18 | Longridge Town | 40 | -30 | 44 |
| 19 | Litherland REMYCA | 40 | -21 | 43 |
| 20 | South Liverpool | 38 | -34 | 33 |
| 21 | Pilkington | 40 | -36 | 33 |
| 22 | Colne | 39 | -43 | 30 |
| 23 | Squires Gate | 41 | -41 | 28 |
| 24 | Prestwich Heys | 40 | -40 | 26 |
| First Division North | P | GD | Pts | |
| 1 | Nelson | 30 | 50 | 70 |
| 2 | Atherton LR | 28 | 34 | 63 |
| 3 | Droylsden | 29 | 29 | 62 |
| 4 | Euxton Villa | 29 | 25 | 57 |
| 5 | Holker Old Boys | 28 | 34 | 56 |
| 6 | Darwen FC | 29 | 13 | 46 |
| 7 | Ashton Town | 29 | 5 | 43 |
| 8 | Maine Road | 29 | 14 | 41 |
| 9 | Bacup Borough | 29 | 10 | 41 |
| 10 | AFC Blackpool * | 28 | 7 | 41 |
| 11 | Ashton Athletic | 29 | -5 | 41 |
| 12 | Maghull | 29 | 0 | 40 |
| 13 | Daisy Hill | 28 | -1 | 38 |
| 14 | Thornton Cleveleys | 29 | -19 | 31 |
| 15 | Steeton | 29 | -22 | 29 |
| 16 | Route One Rovers | 29 | -37 | 22 |
| 17 | Garstang | 30 | -54 | 16 |
| 18 | Skelmersdale United | 29 | -83 | 8 |
| First Division South | P | GD | Pts | |
| 1 | Winsford United | 28 | 50 | 68 |
| 2 | Stafford Town | 28 | 47 | 62 |
| 3 | Sandbach United | 29 | 16 | 58 |
| 4 | Abbey Hulton United | 29 | 32 | 54 |
| 5 | Cheadle Heath Nomads | 29 | 11 | 46 |
| 6 | Alsager Town | 28 | 10 | 45 |
| 7 | Eccleshall | 29 | 4 | 45 |
| 8 | Ashville | 29 | 9 | 43 |
| 9 | Market Drayton Town | 29 | 3 | 38 |
| 10 | Cammell Laird 1907 | 29 | 3 | 38 |
| 11 | New Mills | 30 | -3 | 38 |
| 12 | Stockport Georgians | 28 | -9 | 36 |
| 13 | Runcorn Town | 29 | -10 | 34 |
| 14 | Barnton | 31 | -27 | 32 |
| 15 | Foley Meir | 28 | -19 | 28 |
| 16 | Allscott Heath | 30 | -42 | 26 |
| 17 | Shawbury United | 28 | -31 | 23 |
| 18 | Wolverhampton Sporting Community | 29 | -44 | 21 |
Tables correct as at Mon 10th Mar 2025
